Protein Information

Name erythropoietin
Synonyms EP; EPO; Epoetin; Erythropoietin; Erythropoietin precursor; Epoetins; Erythropoietins; Erythropoietin precursors

Compound Information

Name phosphorus
CAS phosphorus

Reference List

PubMed Abstract RScore(About this table)
20116689 Smith LB, Fadrowski JJ, Howe CJ, Fivush BA, Neu AM, Furth SL: Secondary hyperparathyroidism and anemia in children treated by hemodialysis. Am J Kidney Dis. 2010 Feb;55(2):326-34.

OUTCOMES & MEASUREMENTS: Achievement of serum hemoglobin level > or = 11 g/dL was assessed using Poisson regression adjusting for sex, age, race, dialysis vintage, vascular access type, single-pool Kt/V, serum albumin level, normalized protein catabolic rate, calcium-phosphorus product, and erythropoietin alfa dose.
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19715852 Beltran S, Gavela E, Kanter J, Sancho A, Avila A, Gorriz JL, Crespo JF, Pallardo LM: Beginning hemodialysis: do patients with a failed renal transplant start in worse condition?. Transplant Proc. 2009 Jul-Aug;41(6):2129-31.

RESULTS: We did not observe significant differences in the glomerular filtration rate (GFR), potassium, calcium, phosphorus, albumin, and hemoglobin levels between the 2 groups at the beginning of dialysis.
Erythropoietin resistance index (ERI) was higher in group A.
1(0,0,0,1) Details
19324483 Lee YK, Koo JR, Kim JK, Park II, Joo MH, Yoon JW, Noh JW, Vaziri ND: Effect of route of EPO administration on hemodialysis arteriovenous vascular access failure: a randomized controlled trial. Am J Kidney Dis. 2009 May;53(5):815-22. Epub 2009 Mar 26.

After adjustment for dialysis access type, vascular access age, previous intervention, serum phosphorus level, and diabetes mellitus, subcutaneous EPO administration was independently associated with increased vascular access failure (hazard ratio, 3.56; 95% confidence interval, 1.20 to 10.58; P = 0.02).
Erythropoietin (EPO) potentially can contribute to vascular access stenosis and occlusion by promoting intimal hyperplasia and thrombosis.
1(0,0,0,1) Details
19339410 Bugeja A, Dacouris N, Thomas A, Marticorena R, McFarlane P, Donnelly S, Goldstein M: In-center nocturnal hemodialysis: another option in the management of chronic kidney disease. Clin J Am Soc Nephrol. 2009 Apr;4(4):778-83. Epub 2009 Apr 1.

RESULTS: After conversion to INHD, median values for phosphorus decreased from 5.9 to 3.7 mg/dl (P < 0.01), alkaline phosphatase level increased from 84 to 161 U/L (P < 0.01), and percentage reduction in urea increased from 74 to 89% (P < 0.01).
There was a significant reduction in erythropoietin-stimulating agent use of 1992 U/wk (P < 0.01).
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19516243 Chan KE, Lazarus JM, Wingard RL, Hakim RM: Association between repeat hospitalization and early intervention in dialysis patients following hospital discharge. Kidney Int. 2009 Aug;76(3):331-41. Epub 2009 Jun 10.


Compared to pre-hospitalization values, the levels of hemoglobin, albumin, phosphorus, calcium, and parathyroid hormone and weight were significantly decreased after hospitalization.
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