| Name | protein kinase C (protein family or complex) |
|---|---|
| Synonyms | Protein kinase C; PKC |
| Name | sodium cyanide |
|---|---|
| CAS | sodium cyanide (Na(CN)) |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9319415 | Schwarzbaum P, Bernabeu R, Krumschnabel G, Wieser C: Effect of chemical anoxia on protein kinase C and Na+, K+-ATPase in hepatocytes of goldfish (Carassius auratus) and rainbow trout (Oncorhynchus mykiss). J Exp Biol. 1996;199(Pt 7):1515-21. PKC and Na+/K+-ATPase activities were measured for up to 90 min in the absence (normoxia) and presence (chemical anoxia) of 2 mmol l-1 sodium cyanide. |
2(0,0,0,2) | Details |
| 10381890 | Wu S, Li HY, Wong TM: Cardioprotection of preconditioning by metabolic inhibition in the rat ventricular myocyte. Circ Res. 1999 Jun 25;84(12):1388-95. On blockade of protein kinase C, the delayed cardioprotections of UP and MIP were significantly attenuated. To determine whether opioid receptors (ORs) are involved in the delayed cardioprotection of ischemic preconditioning (IP), the effect of severe metabolic inhibition (MI) with -free buffer that contained sodium cyanide and 2-deoxy- on the viability of isolated rat ventricular myocytes was first determined 20 hours after preconditioning with a sublethal metabolic inhibition (MIP) with -free buffer that contained 2-deoxy- and lactate for 30 minutes in the presence of OR antagonists. |
2(0,0,0,2) | Details |
| 1315244 | Hawes BE, Marzen JE, Waters SB, Conn PM: provokes gonadotrope desensitization to gonadotropin-releasing hormone (GnRH) and gonadotrope sensitization to A23187: evidence for multiple G proteins in GnRH action. Endocrinology. 1992 May;130(5):2465-75. NaF-provoked gonadotrope desensitization to GnRH also occurred in the presence of 3 mM EGTA and in cells which had been depleted of protein kinase C. |
2(0,0,0,2) | Details |
| 16849387 | Bouwman RA, van't Hof FN, de Ruijter W, van Beek-Harmsen BJ, Musters RJ, de Lange JJ, Boer C: The mechanism of sevoflurane-induced cardioprotection is independent of the applied ischaemic stimulus in rat trabeculae. Br J Anaesth. 2006 Sep;97(3):307-14. Epub 2006 Jul 18. BACKGROUND: Sevoflurane protects the myocardium against ischaemic injury through protein kinase C (PKC) activation, mitochondrial K+ATP-channel (mitoK+ATP) opening and production of reactive oxygen species (ROS). |
1(0,0,0,1) | Details |
| 7624870 | Maduh EU, Nealley EW, Song H, Wang PC, Baskin SI: A protein kinase C inhibitor attenuates toxicity in vivo. Toxicology. 1995 Jun 26;100(1-3):129-37. We have examined the effect of pretreatment with a potent protein kinase C (PKC) inhibitor, 1-(5-isoquinoline-sulfonyl)-2-methylpiperazine (H-7), against metabolic alterations induced by sodium cyanide (NaCN), 4.2 mg/kg, in brain of anesthetized male micropigs (6-10 kg). |
1(0,0,0,1) | Details |
| 9571987 | Kiang JG, Ding XZ, McClain DE: Overexpression of HSP-70 attenuates increases in [Ca2+] i and protects human epidermoid A-431 cells after chemical hypoxia. Toxicol Appl Pharmacol. 1998 Apr;149(2):185-94. In this study, we report that cell viability after exposure to NaCN (10 mM, 1 h) is enhanced by the overexpression of HSP-70 resulting from heat shock (45 degrees C, 10 min), treatment with a protein kinase C activator phorbol 12 13- (PMA; 1 microM, 4 h), or HSP-70 cDNA transfection. |
1(0,0,0,1) | Details |
| 15645293 | Mastrodimou N, Lambrou GN, Thermos K: Effect of somatostatin analogues on chemically induced ischaemia in the rat retina. Naunyn Schmiedebergs Arch Pharmacol. 2005 Jan;371(1):44-53. Epub 2005 Jan 12. Eyecups of female Sprague-Dawley rats (250-300 g) were immersed in PBS buffer or PBS containing iodoacetic acid (IAA; 0.5, 5, 50, 100 mM) and sodium cyanide (NaCN; 2.5, 25, 250, 500 mM) (chemical ischaemia solution) for 15, 30, 45, 60, 120 min (pilot study). |
0(0,0,0,0) | Details |