Name | bcl 2 |
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Synonyms | Apoptosis regulator Bcl 2; B cell CLL/lymphoma 2; B cell lymphoma protein 2 alpha; B cell lymphoma protein 2 alpha isoform; BCL2; Bcl 2; B cell CLL/lymphoma 2s; B cell lymphoma protein 2 alphas… |
Name | tetramine |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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17080656 | Wang Y, Shen LH, Chen WJ, Liu M, Li F, Liao ZG: [Expressions of Bcl-2 and Caspase-3 in the internal organs of rats when tetramine was administered]. Fa Yi Xue Za Zhi. 2006 Aug 15;22(4):241-4. OBJECTIVE: To find whether Bcl-2 and Caspase-3 take part in the pathophysiological mechanism of tetramine toxification. |
95(1,1,3,5) | Details |
14513838 | Lombardo MF, Ciriolo MR, Rotilio G, Rossi L: Prolonged triggers apoptosis in SH-SY5Y neuroblastoma cells. Cell Mol Life Sci. 2003 Aug;60(8):1733-43. SH-SY5Y neuroblastoma cells were cultured for up to three serial passages in the presence of the chelator triethylene tetramine (Trien). Mitochondrial antioxidants (Mn superoxide dismutase and Bcl-2) were up-regulated. |
depletion induces expression of antioxidants and 1(0,0,0,1) | Details |
11369509 | Rossi L, Marchese E, Lombardo MF, Rotilio G, Ciriolo MR: Increased susceptibility of neuroblastoma cells to oxidative stress-mediated apoptosis. Free Radic Biol Med. 2001 May 15;30(10):1177-87. Treatment of neuroblastoma cells with the chelator triethylene tetramine tetrahydrochloride induced intracellular decrease of content paralleled by diminished activity of the enzymes Cu, Zn superoxide dismutase, and cytochrome c oxidase. However, molecular markers of apoptosis Bcl-2, p53, and caspase-3 were slightly affected in these cells. |
-deficient 1(0,0,0,1) | Details |