| Name | glutamyl transpeptidase |
|---|---|
| Synonyms | CD224; CD224 antigen; D22S672; D22S732; GGT; GGT 1; GGT1; GGT1 protein… |
| Name | piperonyl butoxide |
|---|---|
| CAS | 5-[[2-(2-butoxyethoxy)ethoxy]methyl]-6-propyl-1,3-benzodioxole |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20035116 | Kawawi M, Saegusa Y, Kemmochi S, Harada T, Shimamoto K, Shibutani M, Mitsumori K: Cytokeratin 8/18 Is a Useful Immunohistochemical Marker for Hepatocellular Proliferative Lesions in Mice. J Vet Med Sci. 2009 Dec 25. In order to clarify whether cytokeratin (CK) 8/18 is a useful immunohistochemical marker for hepatocellular proliferative lesions in mice, partially hepatectomized male ICR mice were given 0.6% piperonyl butoxide (PBO) for 8 (Experiment I) or 25 weeks (Experiment II) after N-diethylnitrosamine (DEN) initiation treatment, and the livers were subjected to histological examinations on hematoxylin and eosin (HE) stained sections, CK8/18 immunohistochemistry and gamma-glutamyl transpeptidase (GGT) histochemistry. |
6(0,0,1,1) | Details |
| 3672539 | Chakrabarti SK, Tuchweber B: Effects of various pretreatments on the acute nephrotoxic potential of styrene in Fischer-344 rats. Toxicology. 1987 Nov;46(3):343-56. Groups of rats were pretreated with either 3-methylcholanthrene (15 mg/kg, i.p., 3 days), or phenobarbital (80 mg/kg, i.p., 3 days), or SKF525-A (50 mg/kg, i.p., 1 h), or piperonyl butoxide (300 mg/kg, i.p., 2 h), or diethylmaleate (400 mg/kg, i.p., 90 min) prior to an i.p. administration of styrene (0, 0.6 and 0.9 g/kg) in corn oil. The uptake of (PAH) by renal cortical slices, the morphology of renal cortices, as well as urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG) and gamma-glutamyl transpeptidase (gamma-GT) of control and pretreated rats were examined 24 h after styrene. |
1(0,0,0,1) | Details |
| 8248953 | Fujitani T, Tanaka T, Hashimoto Y, Yoneyama M: Subacute toxicity of piperonyl butoxide in ICR mice. Toxicology. 1993 Oct 25;83(1-3):93-100. Mice of the 0.9% group of both sexes had increased serum levels of total protein, gamma-glutamyl transpeptidase. |
1(0,0,0,1) | Details |
| 1585383 | Fujitani T, Ando H, Fujitani K, Ikeda T, Kojima A, Kubo Y, Ogata A, Oishi S, Takahashi H, Takahashi O, et al.: Sub-acute toxicity of piperonyl butoxide in F344 rats. Toxicology. 1992;72(3):291-8. Rats of the 2.4%-group had increased levels of albumin, urea and gamma-glutamyl transpeptidase. |
1(0,0,0,1) | Details |
| 19690152 | Kawai M, Saegusa Y, Jin M, Dewa Y, Nishimura J, Harada T, Shibutani M, Mitsumori K: Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice. Toxicol Pathol. 2009;37(6):761-9. Epub 2009 Aug 18. The incidence of gamma-glutamyl transpeptidase (GGT)-positive foci and PCNA-positive cells was significantly increased in the DEN + PBO group compared with the DEN-alone group. |
1(0,0,0,1) | Details |
| 18243470 | Rankin GO, Hong SK, Anestis DK, Ball JG, Valentovic MA: Mechanistic aspects of 4-amino-2,6-dichlorophenol-induced in vitro nephrotoxicity. Toxicology. 2008 Mar 12;245(1-2):123-9. Epub 2007 Dec 27. Inhibitors of CYP piperonyl butoxide and isoniazid) and FMO activity modulators (methimazole, N-octylamine) had no effect on ADCP cytotoxicity. |
0(0,0,0,0) | Details |