Protein Information

ID 2203
Name secretory leukocyte protease inhibitor
Synonyms ALK1; ALP; Alk1; Antileukoprotease; Antileukoproteinase 1; Antileukoproteinase 1 precursor; BLPI; HUSI…

Compound Information

ID 983
Name DMPA
CAS

Reference

PubMed Abstract RScore(About this table)
18155704 Li A, Felix JC, Yang W, Jain JK: Effect of mifepristone on the expression of endometrial secretory leukocyte protease inhibitor in new medroxyprogesterone acetate users. Fertil Steril. 2008 Sep;90(3):872-5. Epub 2007 Dec 26.
The effect of mifepristone on the expression of secretory leukocyte protease inhibitor (SLPI) in the endometrium of women using depot medroxyprogesterone acetate (DMPA) was investigated in this randomized, placebo-controlled trial. The study showed that the administration of DMPA led to a substantial inhibition of endometrial SLPI protein and mRNA, and that the addition of mifepristone to DMPA-exposed endometrium partially restored the expression of glandular SLPI.
88(1,1,2,3)