Protein Information

ID 179
Name prothrombin
Synonyms Coagulation factor II; Coagulation factor II variant; F2; F2 protein; F2 protein precursor; Factor II; PT; Prothrombin…

Compound Information

ID 1771
Name difenacoum
CAS

Reference

PubMed Abstract RScore(About this table)
1361149 Butcher GP, Shearer MJ, MacNicoll AD, Kelly MJ, Ind PW: Difenacoum poisoning as a cause of haematuria. Hum Exp Toxicol. 1992 Nov;11(6):553-4.
A man presented with frank haematuria and a grossly prolonged prothrombin time. He was later found to have taken an overdose of difenacoum--a 'superwarfarin' rodenticide. The diagnosis was confirmed by a serum concentration of difenacoum of 0.6 micrograms ml-1. Overdosage with superwarfarins is discussed and the need for prolonged treatment with vitamin K1 highlighted.
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