| 8255354 |
Yadid G, Maor G, Youdim MB, Silberman M, Zinder O: Autoradiographic localization of strychnine-sensitive glycine receptor in bovine adrenal medulla. Neuroreport. 1994 Mar 21;5(7):777-80.
The presence of an uptake system and a functional glycine receptor in adrenal medulla chromaffin cells was investigated using an autoradiographic technique in adrenal gland slices. Specific 3 [H] glycine binding was observed in both adrenal cortex and medulla slices, while only specific binding of [3H] strychnine was seen only in chromaffin cells and was not associated with cortical cells. [3H] Glycine binding sites in the cortex are apparently different from those of [3H] strychnine binding sites in the medulla since excess strychnine does not displace [3H] glycine from adrenal cortex but does so from medulla. This difference supports biochemical evidence for glycine transport into medulla cells and glycine receptor sites on the chromaffin cell membrane. |
8(0,0,1,3) |