| 15665918 |
Nikitin AA, Abidov MT, Kovalevskaya EO, Kalyuzhin OV: Search for potent modulators of cytokine production by macrophages. . Bull Exp Biol Med. 2004 Sep;138(3):259-61.
We compared the effects of Tamerit, Polyoxidony, and Licopid on spontaneous and lipopolysaccharide-stimulated production of interleukin-1 and tumor necrosis factor by mouse peritoneal macrophages in vitro. The test preparations were equally potent in stimulating nonactivated cells. Licopid produced a costimulatory effect on macrophages primed with endotoxin. Tamerit in different doses suppressed cytokine production by cells. Polyoxidony in low doses activated, but in high doses suppressed this process. |
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