prothrombin

General Information (Source: NCBI Gene,UniProt)

Text mining Term prothrombin
UniProt ID Q3TJ94_MOUSE
Name Coagulation factor II
Gene Names F2
Taxonomy Mus musculus

General annotation

Function
Subcellular location

Gene Ontology

GO:0030168 platelet activation BP
GO:0004252 serine-type endopeptidase activity MF
GO:0005509 calcium ion binding MF
GO:0008284 positive regulation of cell proliferation BP
GO:0008360 regulation of cell shape BP
GO:0006508 proteolysis BP
GO:0030307 positive regulation of cell growth BP

Sequence

>gi|6753798|ref|NP_034298.1| prothrombin [Mus musculus]
MSHVRGLGLPGCLALAALVSLVHSQHVFLAPQQALSLLQRVRRANSGFLEELRKGNLERECVEEQCSYEE
AFEALESPQDTDVFWAKYTVCDSVRKPRETFMDCLEGRCAMDLGVNYLGTVNVTHTGIQCQLWRSRYPHK
PEINSTTHPGADLKENFCRNPDSSTTGPWCYTTDPTVRREECSVPVCGQEGRTTVVMTPRSGGSKDNLSP
PLGQCLTERGRLYQGNLAVTTLGSPCLPWNSLPAKTLSKYQDFDPEVKLVENFCRNPDWDEEGAWCYVAG
QPGDFEYCNLNYCEEAVGEENYDVDESIAGRTTDAEFHTFFNEKTFGLGEADCGLRPLFEKKSLKDTTEK
ELLDSYIDGRIVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL
VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWRENLDRDIALLKLKKPVPFSDYIHPVCLPDKQTVTSLL
RAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVERPVCKASTRIRITDNMFCAGFKVNDTKRGDA
CEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRKGKYGFYTHVFRLKRWIQKVIDQFG

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Mm.89048
PDB
RefSeq NP_034298.1
Pfam PF00089
PF00594
PF00051
PF09396