alpha 1 acid glycoprotein

General Information (Source: NCBI Gene,UniProt)

Text mining Term alpha 1 acid glycoprotein
UniProt ID A1AG_RAT
Name OMD
Alpha-1-acid glycoprotein
Orosomucoid
Gene Names Orm1
Taxonomy Rattus norvegicus

General annotation

Function Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain (By similarity). Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Subcellular location Secreted (By similarity).

Gene Ontology

GO:0002682 regulation of immune system process BP
GO:0033197 response to vitamin E BP
GO:0008144 drug binding MF
GO:0071378 cellular response to growth hormone stimulus BP
GO:0042493 response to drug BP
GO:0006953 acute-phase response BP
GO:0005615 extracellular space CC
GO:0002438 acute inflammatory response to antigenic stimulus BP
GO:0031100 organ regeneration BP
GO:0014070 response to organic cyclic compound BP
GO:0071385 cellular response to glucocorticoid stimulus BP
GO:0032496 response to lipopolysaccharide BP
GO:0006810 transport BP
GO:0002439 chronic inflammatory response to antigenic stimulus BP
GO:0071300 cellular response to retinoic acid BP

Sequence

>gi|16757980|ref|NP_445740.1| alpha-1-acid glycoprotein precursor [Rattus norvegicus]
MALHMVLVVLSLLPLLEAQNPEPANITLGIPITNETLKWLSDKWFYMGAAFRDPVFKQAVQTIQTEYFYL
TPNLINDTIELREFQTTDDQCVYNFTHLGVQRENGTLSKCAGAVKIFAHLIVLKKHGTFMLAFNLTDENR
GLSFYAKKPDLSPELRKIFQQAVKDVGMDESEIVFVDWTKDKCSEQQKQQLELEKETKKETKKDP

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Database Cross Reference

Ensembl Gene ENSRNOT00000010454
UniGene Rn.10295
PDB
RefSeq NP_445740.1
Pfam PF00061