pg m

General Information (Source: NCBI Gene,UniProt)

Text mining Term pg m
UniProt ID CSPG2_RAT
Name Chondroitin sulfate proteoglycan 2
Chondroitin sulfate proteoglycan core protein 2
GHAP
Glial hyaluronate-binding protein
Versican core protein
PG-M
Large fibroblast proteoglycan
Gene Names Vcan
Synonyms:Cspg2
Taxonomy Rattus norvegicus

General annotation

Function May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid.
Subcellular location Secreted, extracellular space, extracellular matrix.

Gene Ontology

GO:0031103 axon regeneration BP
GO:0005529 sugar binding MF
GO:0005540 hyaluronic acid binding MF
GO:0005509 calcium ion binding MF
GO:0005578 proteinaceous extracellular matrix CC
GO:0030169 low-density lipoprotein particle binding MF
GO:0007155 cell adhesion BP

Sequence

>gi|281604092|ref|NP_001164030.1| versican core protein isoform 4 precursor [Rattus norvegicus]
MLINMNGILWMCSTLLLTHALHKAKMEENPPVKGSLSGKVILPCHFSTLPTLPPDYNTSEFLRIKWSKIE
VDKNGKDIKETTVLVAQDGNIKIGQDYKGRVSVPTHPDDVGDASLTMVKLRASDAGVYRCDVMYGIEDTQ
NTMSLAVDGVVFHYRAATSRYTLNFESAQQACLDIGAVIATPEQLFAAYEDGFEQCDAGWLSDQTVRYPI
RAPREGCYGDMMGKEGVRTYGFRSPQETYDVYCYVDHLDGDVFHITAPSKFTFEEAEAECANRDARLATV
GELHAAWRNGFDQCDYGWLSDASVRHPVTVARAQCGGGLLGVRTLYRFENQTCFPLPDSRFDAYCFKRPD
LCKTNPCLNGGTCYPTETSYVCTCAPGYSGDQCELDFDECHSNPCRNGATCVDGLNTFRCLCLPSYVGAL
CEQDTETCDYGWHKFQGQCYKYFAHRRTWDAAERECRLQGAHLTSILSHEEQMFVNRVGHDYQWIGLNDK
MFEHDFRWTDGSALQYENWRPNQPDSFFSAGEDCVVIIWHENGQWNDVPCNYHLTYTCKKGTVACGQPPV
VENAKTFGKMKPRYEINSLIRYHCKDGFIQRHLPTIRCLGNGRWAMPKITCMNPSAYQRTYSKKYLKNSS
SVKDNSINTSKHEHRWSRRWQETRR

Options for BLAST

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Database Cross Reference

Ensembl Gene
UniGene Rn.35666
PDB
RefSeq NP_001164030.1
NP_001164031.1
NP_001164029.1
Pfam PF07686
PF00059
PF00084
PF00193
PF00008