calcium channel (protein family or complex)

General Information (Source: NCBI Gene,UniProt)

Text mining Term calcium channel (protein family or complex)
UniProt ID FLOWR_DROSI
Name Calcium channel flower
Gene Names flower
Taxonomy Drosophila simulans

General annotation

Function A calcium channel that regulates synaptic endocytosis and hence couples exo- with endocytosis. Required in the nervous system and necessary in photoreceptor cells (By similarity).
Subcellular location Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein (By similarity). Note=Upon fusion of the synaptic vesicle with the presynaptic membrane, protein is present in the periactive zones, where endocytosis is known to occur (By similarity).

Gene Ontology

GO:0046530 photoreceptor cell differentiation BP
GO:0030054 cell junction CC
GO:0030285 integral to synaptic vesicle membrane CC
GO:0005262 calcium channel activity MF
GO:0048488 synaptic vesicle endocytosis BP

Sequence

>gi|269969354|sp|B4QLP9.1|FLOWR_DROSI RecName: Full=Calcium channel flower
MSFAEKITGLLARPNQQDPIGPEQPWYLKYGSRWLGIVAAFFAILFGLWNVFSIITLSVSCLVAGIIQMV
AGFVVMLLEAPCCFVCFEQVNVIADKVDSKPLYFRAGLYIAMAIPPIILCFGLASLFGSGLIFGTGVVYG
MMALGKKASAEDMRAAAQQTFGGNTPAQTNDRAGIVNNAQPFSFTGAVGTDSNV

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Database Cross Reference

Ensembl Gene
UniGene Dsi.7985
PDB
RefSeq XP_002085013.1
Pfam PF10233