lufenuron

Identification (Source:EPA,EU)

ID 1417
Name lufenuron
CAS 103055-07-8
IUPAC
Inchi InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)
CIPAC 704
EPA Code
Formula C17H8Cl2F8N2O3
SMILES Clc1cc(c(Cl)cc1OC(F)(F)C(F)C(F)(F)F)NC(=O)NC(=O)c2c(F)cccc2F
Status Approved

Classification

Mode of Action Systemic, selective, stomach acting, chitin synthesis inhibitor
Pesticide Type Insecticide, Acaricide, Veterinary treatment
Chemical Group Benzoylurea
Classification benzoylphenylurea chitin synthesis inhibitors
chitin synthesis inhibitors

Properties (Source:PubChem)

Molecular Weight 511.16
Physical State White solid
AlogP 6.538
H-Bond Donor 2
H-Bond Acceptor 3
Surface Area 399.14
Polar Surface Area 67.43

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Acute 72 hour EC50, growth 8.8 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.0001 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.0013 mg l-1
Birds Acute LD50 2000 mg kg-1
Birds Short term dietary LC50/LD50 966 mg/kg bw/day
Earthworms Acute 14 day LD50 > 500 mg kg-1
Fish Acute 96 hour LC50 > 29 mg l-1
Fish Chronic 21 day NOEC 0.02 mg l-1
Honeybees Acute 48 hour LD50 > 197 μg bee-1
Mammals Acute oral LD50 > 2000 mg kg-1
Mammals Short term dietary NOEL 2 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.002 mg kg-1
Sediment dwelling organisms Chronic 28 day NOEC, sediment 0.04 mg kg-1
Bio-concentration factor BCF 5300
Bio-concentration factor CT50 36 days

Related targets

Target Name RScore (About this table)
cytochrome P450 (protein family or complex) 33(0,1,1,3) Details
C18 4(0,0,0,4) Details
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