triazophos

Identification (Source:EPA,EU)

ID 244
Name triazophos
CAS 24017-47-8
IUPAC
Inchi InChI=1S/C12H16N3O3PS/c1-3-16-19(20,17-4-2)18-12-13-10-15(14-12)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3
CIPAC 353
EPA Code 344600
Formula C12H16N3O3PS
SMILES CCOP(=S)(OCC)OC1=NN(C=N1)C2=CC=CC=C2
Status Not Approved

Classification

Mode of Action Non-systemic, broad spectrum with contact and stomach action. Acetylcholinesterase (AChE) inhibitor.
Pesticide Type Insecticide, Acaricide, Nematicide
Chemical Group Organophosphate
Classification organothiophosphate nematicides
heterocyclic organothiophosphate insecticides
triazole organothiophosphate insecticides
organothiophosphate insecticides
organothiophosphate acaricides

Properties (Source:PubChem)

Molecular Weight 313.3
Physical State Yellow-brown oily liquid
AlogP 3.072
H-Bond Donor 0
H-Bond Acceptor 6
Surface Area 294.76
Polar Surface Area 100.3

Structure



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3D similarity method

2D similarity method

Compound Database



Bioactivity Database

KEGG (5,928)

PDB (7,072)


Similarity Threshold

Ecotoxicology (Source:PPDB,IPM)

Species Method Study Time Dose Type Value
Algae Chronic 96 hour NOEC, growth 0.1 mg l-1
Algae Acute 72 hour EC50, growth 9.1 mg l-1
Aquatic invertebrates Acute 48 hour EC50 0.0026 mg l-1
Aquatic invertebrates Chronic 21 day NOEC 0.01 mg l-1
Birds Acute LD50 8.3 mg kg-1
Earthworms Acute 14 day LD50 466 mg kg-1
Fish Acute 96 hour LC50 0.038 mg l-1
Fish Chronic 21 day NOEC 0.0005 mg l-1
Honeybees Acute 48 hour LD50 14.35 μg bee-1
Mammals Acute oral LD50 66 mg kg-1
Mammals Short term dietary NOEL 1.5 mg kg-1
Mammals Short term dietary NOEL 20 ppm diet
Bio-concentration factor BCF 300
Bio-concentration factor CT50 Not available days

Related targets

Target Name RScore (About this table)
AChEs 61(0,1,3,21) Details
alkaline phosphatase 32(0,1,1,2) Details
catalase 31(0,1,1,1) Details
superoxide dismutase 31(0,1,1,1) Details
glutathione S transferase 31(0,1,1,1) Details
acid phosphatase 31(0,1,1,1) Details
factor A 31(0,1,1,1) Details
cholinesterases 19(0,0,2,9) Details
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