Protein Information

Name cytochrome P450 (protein family or complex)
Synonyms cytochrome P450; cytochrome P 450; CYP450; CYP 450

Compound Information

Name trinexapac
CAS 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid

Reference List

PubMed Abstract RScore(About this table)
19581023 Villa-Ruano N, Betancourt-Jimenez MG, Lozoya-Gloria E: Biosynthesis of uterotonic diterpenes from Montanoa tomentosa (zoapatle). J Plant Physiol. 2009 Dec 15;166(18):1961-7. Epub 2009 Jul 5.


Our results suggest the biosynthetic conversion of KA into GF by a putative cytochrome P450-like desaturase.
2(0,0,0,2) Details
15012200 Rademacher W: GROWTH RETARDANTS: Effects on Gibberellin Biosynthesis and Other Metabolic Pathways. Annu Rev Plant Physiol Plant Mol Biol. 2000 Jun;51:501-531.

These retardants block cytochrome P450-dependent monooxygenases, thereby inhibiting oxidation of ent-kaurene into ent-kaurenoic acid. (c) Structural mimics of 2-oxoglutaric acid, which is the co-substrate of dioxygenases that catalyze late steps of GA formation.
Acylcyclohexanediones, e.g. prohexadione-Ca and trinexapac-ethyl and daminozide, block particularly 3ss-hydroxylation, thereby inhibiting the formation of highly active GAs from inactive precursors, and (d) 16,17-Dihydro-GA5 and related structures act most likely by mimicking the GA precursor substrate of the same dioxygenases.
1(0,0,0,1) Details