Protein Information

Name glutamate receptors (protein family or complex)
Synonyms Glutamate receptor; Glutamate receptors

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
20096330 Rush T, Liu XQ, Hjelmhaug J, Lobner D: Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture. Neuroscience. 2010 Mar 31;166(3):899-906. Epub 2010 Jan 20.

The toxicity of chlorpyrifos was attenuated by antagonists of either the NMDA or AMPA/kainate-type glutamate receptors, but the cell death was potentiated by the caspase inhibitor ZVAD.
81(1,1,1,1) Details
19440498 Slotkin TA, Seidler FJ: Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. Environ Health Perspect. 2009 Apr;117(4):587-96. Epub 2008 Dec 5.

METHODS: We used PC12 cells as a model of developing neurons and evaluated transcriptional profiles for genes for oxidative stress responses and glutamate receptors.
2(0,0,0,2) Details