Protein Information

Name E cadherin
Synonyms Arc 1; CAM 120/80; CD324; CD324 antigen; CDH 1; CDH1; CDHE; Cadherin 1…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
11744161 Yang J, Mutkus LA, Sumner D, Stevens JT, Eldridge JC, Strandhoy JW, Aschner M: Transendothelial permeability of chlorpyrifos in RBE4 monolayers is modulated by astrocyte-conditioned medium. Brain Res Mol Brain Res. 2001 Dec 16;97(1):43-50.

Immunohistochemical studies showed positive staining in RBE4 cells for E-cadherin, a Ca (2+)-dependent cell-cell adhesion molecule.
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15527875 Parran DK, Magnin G, Li W, Jortner BS, Ehrich M: Chlorpyrifos alters functional integrity and structure of an in vitro BBB model: co-cultures of bovine endothelial cells and neonatal rat astrocytes. Neurotoxicology. 2005 Jan;26(1):77-88.

The co-culturing of BMECs and astrocytes resulted in tight junction formation as determined by electron microscopy, electrical resistance and western blot analysis of two tight junction-associated proteins (ZO-1 and e-cadherin).
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