| Name | superoxide dismutase |
|---|---|
| Synonyms | IPO B; Indophenoloxidase B; MNSOD; Manganese superoxide dismutase; Manganese containing superoxide dismutase; Mangano superoxide dismutase; Mn superoxide dismutase; Mn SOD… |
| Name | chlorpyrifos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 12099624 | Oncu M, Gultekin F, Karaoz E, Altuntas I, Delibas N: Nephrotoxicity in rats induced by chlorpryfos-ethyl and ameliorating effects of antioxidants. Hum Exp Toxicol. 2002 Apr;21(4):223-30. Nephrotoxicity induced by chlorpyrifos-ethyl (CE) and ameliorating effects of and plus were evaluated in rats exposed to CE. The levels of thiobarbituric acid reactive substance (TBARS) and antioxidant potential (AOP), and the activities of peroxidase (GSH-Px), catalase (CAT) and superoxide dismutase (SOD) were studied in the homogenates of kidney tissue. |
1(0,0,0,1) | Details |
| 20028704 | Mansour SA, Mossa AH: Adverse effects of lactational exposure to chlorpyrifos in suckling rats. Hum Exp Toxicol. 2010 Feb;29(2):77-92. Epub 2009 Dec 22. Exposure of the mothers to CPF caused increase in lipid peroxidation (LPO) and decrease in superoxide dismutase (SOD) and glutathione-s-transferase (GST) in lactating pups. |
1(0,0,0,1) | Details |
| 11354911 | Gultekin F, Delibas N, Yasar S, Kilinc I: In vivo changes in antioxidant systems and protective role of and a combination of and on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats. Arch Toxicol. 2001 Apr;75(2):88-96. Levels of thiobarbituric acid reactive substance (TBARS), antioxidant defence potential (AOP), and the activities of superoxide dismutase (SOD), peroxidase (GSH-Px), and catalase (CAT) were determined in erythrocytes. |
1(0,0,0,1) | Details |
| 18584359 | Samarawickrema N, Pathmeswaran A, Wickremasinghe R, Peiris-John R, Karunaratna M, Buckley N, Dawson A, de Silva J: Fetal effects of environmental exposure of pregnant women to organophosphorus compounds in a rural farming community in Sri Lanka. Clin Toxicol. 2008 Jul;46(6):489-95. METHODS: Toxicity was assessed by measuring (i) OPC levels in breast milk and plasma from maternal and cord blood using gas chromatography, (ii) maternal and fetal butyrylcholinesterase (BChE) activity using inhibition assays, (iii) antioxidant status of the fetus using superoxide dismutase activity assays, (iv) oxidative stress in the fetus by determining malondialdehyde (MDA) concentrations, and (v) examining for fetal DNA fragmentation using electrophoresis. RESULTS: Organophosphate residues were detected in only two subjects (chlorpyrifos in maternal and cord blood of one during the spray season and dimethoate in breast milk of another during the in between spray season), but the test employed was capable of only detecting concentrations above 0.05 mg/l. |
1(0,0,0,1) | Details |
| 11131033 | Gultekin F, Ozturk M, Akdogan M: The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro). Arch Toxicol. 2000 Nov;74(9):533-8. After incubation, the levels of malondialdehyde (MDA) and the activity of superoxide dismutase (SOD), peroxidase (GSH-Px), and catalase (CAT) were determined in the erythrocytes in all tubes. |
1(0,0,0,1) | Details |
| 16539209 | Gultekin F, Patat S, Akca H, Akdogan M, Altuntas I: can suppress the cytotoxic effects of chlorpyrifos on human hepG2 cell lines. Hum Exp Toxicol. 2006 Feb;25(2):47-55. The level of thiobarbituric acid reactive substance (TBARS) and the activities of superoxide dismutase (SOD), peroxidase (GSH-Px) and catalase (CAT) were determined in cell lines with or without administration to find out the possible mechanism of |
1(0,0,0,1) | Details |
| 19440498 | Slotkin TA, Seidler FJ: Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent in PC12 cells. Environ Health Perspect. 2009 Apr;117(4):587-96. Epub 2008 Dec 5. |
0(0,0,0,0) | Details |
| 17974266 | Zhang YL, Mu W, Chen ZL, Han ZR, Ma C, Zhai RH: [Susceptibility and related physiological and biochemical mechanisms of Carposina niponensis Walsingham larvae on six insecticides before and after overwintering]. Ying Yong Sheng Tai Xue Bao. 2007 Aug;18(8):1913-6. The study with impregnating method showed that after overwintering, the susceptibility of Carposina niponensis larvae on triazophos, phoxim, chlorpyrifos, malathion, lambda-cyhalothrin and abamectin was 34.50, 16.71, 3.89, 3.28, 5.90 and 2.73 times as much as that before overwintering, the total protein, and fat contents and carboxylesterase, acid phosphatase, alkaline phosphatase, glutathione-S-transferase, superoxide dismutase, catalase and peroxidase activities in C. niponensis larvae were decreased by 17.10%, 41.76% and 30.08%, 62.36%, 53.47%, 76.19%, 80.60%, 18.77%, 14.16% and 64.02%, respectively, and the activity of acetylcholinesterase, the target enzyme of many insecticides, was 1.41 times as much as that before overwintering. |
31(0,1,1,1) | Details |
| 16169541 | Goel A, Dani V, Dhawan DK: Protective effects of zinc on lipid peroxidation, antioxidant enzymes and hepatic histoarchitecture in chlorpyrifos-induced toxicity. Chem Biol Interact. 2005 Oct 20;156(2-3):131-40. Chlorpyrifos treatment resulted in a significant increase in hepatic lipid peroxidation and activities of superoxide dismutase (SOD), peroxidase (G-Px) and glutathione reductase (GR). |
6(0,0,1,1) | Details |
| 18222074 | Yu F, Wang Z, Ju B, Wang Y, Wang J, Bai D: Apoptotic effect of organophosphorus insecticide chlorpyrifos on mouse retina in vivo via oxidative stress and protection of combination of vitamins C and E. Exp Toxicol Pathol. 2008 Apr;59(6):415-23. Epub 2008 Jan 25. Cell apoptosis, lipid peroxidation and DNA damage were increased, and activities of antioxidant enzymes superoxide dismutase, catalase and peroxidase were decreased in retina of chlorpyrifos-administrated mice (63mg/kg, single treatment, via oral gavage). |
6(0,0,1,1) | Details |
| 19365751 | Panemangalore M, Bebe FN: Short- and long-term exposure to low levels of pesticide and mixtures modify endogenous antioxidants in tissues of rats. J Environ Sci Health B. 2009 May;44(4):357-64. Two experiments were conducted using dietary (F) and oral pesticide (P) mixtures (FM, PM) on changes in the activities of superoxide dismutase (SOD), peroxidase (GPX) and concentrations (GSH) in male Sprague Dawley rats (150-175 g) fed for 2 or 4 weeks the AIN 93M diet with or without equal amounts of rutin, (FM) at 1.0 mM or 5 mM/kg diet, and with/without PM fed orally at 0.1 mL/d/5d/wk (PM = chlorpyrifos, endosulfan, thiram at 25% LD (50) in oil). |
6(0,0,1,1) | Details |
| 12716052 | Bebe FN, Panemangalore M: Exposure to low doses of endosulfan and chlorpyrifos modifies endogenous antioxidants in tissues of rats. J Environ Sci Health B. 2003 May;38(3):349-63. Two experiments were conducted in male SD rats (225-250 g) to determine changes in the activities of endogenous antioxidants superoxide dismutase (SOD), catalase (CAT), peroxidase (GPX) and concentrations of (GSH) in tissues after exposure to low doses of endosulfan and chlorpyrifos using a whole body exposure technique. |
6(0,0,1,1) | Details |
| 14718179 | Ehrich M, Hancock S, Ward D, Holladay S, Pung T, Flory L, Hinckley J, Jortner BS: Neurologic and immunologic effects of exposure to chlorpyrifos, and multiple doses of tri-ortho-tolyl over a 28-day period in rats. J Toxicol Environ Health A. 2004 Mar 12;67(5):431-57. In addition, choline acetyltransferase, glial acidic fibrillary protein (GFAP), peroxidase, and superoxide dismutase were evaluated in one or more of the brain regions already identified. |
2(0,0,0,2) | Details |
| 12211644 | Karaoz E, Gultekin F, Akdogan M, Oncu M, Gokcimen A: Protective role of and a combination of and on lung toxicity induced by chlorpyrifos-ethyl in rats. Exp Toxicol Pathol. 2002 Aug;54(2):97-108. In tissue homogenates, the level of thiobarbituric acid reactive substances (TBARS), antioxidant potential (AOP), and the activities of superoxide dismutase (SOD), peroxidase (GSH-Px) and catalase (CAT) were determined. |
1(0,0,0,1) | Details |