| Name | caspase 3 |
|---|---|
| Synonyms | Apopain; CASP 3; CASP3; CPP 32; CPP32; CPP32B; Caspase 3; Caspase 3 precursor… |
| Name | chlorpyrifos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18996166 | Li Q, Kobayashi M, Kawada T: Chlorpyrifos induces apoptosis in human T cells. . Toxicology. 2009 Jan 8;255(1-2):53-7. Epub 2008 Oct 17. These findings indicate that chlorpyrifos can induce apoptosis in human Jurkat T cell cells, and this effect is partially mediated by the activation of intracellular caspase-3. |
118(1,2,3,3) | Details |
| 16787693 | Nakadai A, Li Q, Kawada T: Chlorpyrifos induces apoptosis in human monocyte cell line U937. Toxicology. 2006 Jul 25;224(3):202-9. Epub 2006 May 9. These findings indicate that chlorpyrifos can induce apoptosis in U937 cells, and this effect is partially mediated by activation of intracellular caspase-3. |
118(1,2,3,3) | Details |
| 19326769 | Das PC, Cao Y, Roset RL, Cherrington N, Hodgson E: Enzyme induction and cytotoxicity in human hepatocytes by chlorpyrifos and N,N-diethyl-m-toluamide (DEET). Drug Metabol Drug Interact. 2008;23(3-4):237-60. DEET is a mild, while chlorpyrifos is a relatively potent, inducer of kinase and caspase-3/7, an indicator of apoptosis, while inducing 15-20% and 25-30% cell death, respectively. |
81(1,1,1,1) | Details |
| 17681413 | Li Q, Kobayashi M, Kawada T: Organophosphorus pesticides induce apoptosis in human NK cells. Toxicology. 2007 Sep 24;239(1-2):89-95. Epub 2007 Jul 5. NK-92CI and/or NK-92MI were treated with dichlorvos (DDVP) or chlorpyrifos (CP) at 0-100 ppm for 1-72 h at 37 degrees C in vitro. Apoptosis induced by DDVP and CP was determined by FITC-Annexin V staining and the intracellular level of active caspase-3 was analysed by flow cytometry. |
2(0,0,0,2) | Details |
| 19167454 | Saulsbury MD, Heyliger SO, Wang K, Johnson DJ: Chlorpyrifos induces oxidative stress in oligodendrocyte progenitor cells. Toxicology. 2009 May 2;259(1-2):1-9. Epub 2009 Jan 9. Moreover, CPF toxicity is associated with nuclear condensation and elevation of caspase 3/7 activity and Heme oxygenase-1 mRNA expression. |
1(0,0,0,1) | Details |