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Quistad GB, Liang SN, Fisher KJ, Nomura DK, Casida JE: Each lipase has a unique sensitivity profile for organophosphorus inhibitors. Toxicol Sci. 2006 May;91(1):166-72. Epub 2006 Jan 31.
Postheparin serum lipase, lipoprotein lipase (LPL) (two sources), pancreatic lipase, monoacylglycerol (MAG) lipase, cholesterol esterase, and KIAA1363 are considered with 32 OP pesticides and related compounds.
Postheparin lipolytic activity in rat serum is inhibited by 14 OPs, including chlorpyrifos oxon (IC50 50-97 nM). |
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