Protein Information

Name DTNB
Synonyms Beta dystrobrevin; DTN B; DTNB; Dystrobrevin beta; Dystrobrevin betas

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
8829340 Willig S, Hunter DL, Dass PD, Padilla S: Validation of the use of 6,6'-dithiodinicotinic acid as a chromogen in the Ellman method for cholinesterase determinations. Vet Hum Toxicol. 1996 Aug;38(4):249-53.


The Ellman method for cholinesterase determination is a spectrophotometric method which entails the use of 5,5'-dithiobis-(2-nitrobenzoic) acid (DTNB) as a chromogen and records the level of cholinesterase activity as the change in absorbance at 412 nm.
2(0,0,0,2) Details
20021020 Das GP, Jamil K, Rahman MF: Effect of four organophosphorus compounds on human blood acetylcholinesterase: in vitro studies. Toxicol Mech Methods. 2006;16(8):455-9.

The aim of the study was to determine the IC50 concentration of the pesticides monocrotophos, chlorpyrifos, profenofos, and acephate as inhibitors of AChE.
Cholinesterase was spectrophotometrically measured using acetylthiocholine iodide (AChI) as substrate and dithiobisnitrobenzoic acid (DTNB) as the coloring agent using different aliquots of the pesticides.
1(0,0,0,1) Details