Protein Information

Name CA3
Synonyms CA III; Carbonic anhydrase C; CA3; CAIII; Car3; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
19353435 Mitra NK, Nadarajah VD, Siong HH: Effect of concurrent application of heat, swim stress and repeated dermal application of chlorpyrifos on the hippocampal neurons in mice. Folia Neuropathol. 2009;47(1):60-8.

Neurons of CA3 and CA1 regions of the hippocampus showed significant reduction in neuronal counts in (s) E1 and (s) E2 groups compared to E1 and E2 groups.
2(0,0,0,2) Details
20137303 Chen XP, Jin JL, Li CW, Wang FS: [Effects of low concentration of chlorpyrifos prenatal exposure on generation mouse brain hippocampus and somatosensory cortex]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2009 Sep;27(9):557-9.

On postnatal day (PD) 35, quantitative morphologic examines were measured in CA1, CA3, dentate gyrus regions of the hippocampus and somatosensory cortex.
2(0,0,0,2) Details
15763277 Roy TS, Sharma V, Seidler FJ, Slotkin TA: Quantitative morphological assessment reveals neuronal and glial deficits in hippocampus after a brief subtoxic exposure to chlorpyrifos in neonatal rats. Brain Res Dev Brain Res. 2005 Mar 22;155(1):71-80.

On PN15 and 20, we conducted quantitative morphologic examinations of neurons and glia in CA1, CA3, and dentate gyrus regions of the hippocampus.
2(0,0,0,2) Details
17321052 Prendergast MA, Self RL, Smith KJ, Ghayoumi L, Mullins MM, Butler TR, Buccafusco JJ, Gearhart DA, Terry AV Jr: Microtubule-associated targets in chlorpyrifos oxon hippocampal neurotoxicity. Neuroscience. 2007 Apr 25;146(1):330-9. Epub 2007 Feb 22.

Concentration-dependent injury in the cornu ammonis (CA) 1 pyramidal cell layer and to a lesser extent, CA3 and dentate cells, was evident 3 days after the start of CPO exposure (> or=0.1 microM) and was greatest after 7 days.
1(0,0,0,1) Details