Protein Information

Name transferase
Synonyms 4' phosphopantetheinyl transferase; 4' phosphopantetheinyl transferase; AASD PPT; AASDHPPT; AASDPPT; Alpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferase; Aminoadipate semialdehyde dehydrogenase phosphopantetheinyl transferase; CGI 80…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
16334264 Tilak KS, Veeraiah K, Rao DK: Biochemical changes induced by chlorpyrifos, an organophosphate compound in sublethal concentrations to the freshwater fish Catla catla, Labeo rohita and Cirrhinus mrigala. J Environ Biol. 2005 Jun;26(2 Suppl):341-7.

Biochemical changes in total glycogen, total proteins, lactate dehydrogenase (LDH), alanine amino transferase (ALAT) and aspartate amino transferase (AAT) and nucleic acids, Deoxy and ribose, were estimated in the tissues of fishes exposed to the toxicant chlorpyrifos technical grade.
6(0,0,1,1) Details
7722883 Lodovici M, Aiolli S, Monserrat C, Dolara P, Medica A, Di Simplicio P: Effect of a mixture of 15 commonly used pesticides on DNA levels of 8-hydroxy-2-deoxyguanosine and xenobiotic metabolizing enzymes in rat liver. J Environ Pathol Toxicol Oncol. 1994;13(3):163-8.

The level of 8-OH-2-deoxyguanosine in rat liver DNA was measured as an index of oxidative damage after treating rats for 10 days at a dose ranging from 0.75 to 10 mg/kg with a mixture of 15 pesticides (dithiocarbamate, benomyl, thiabendazole, diphenylamine, chlorthalonil, procimidone, methidathion, chlorpyrifos-ethyl, fenarimol, parathion-methyl, chlorpropham, parathion, vinclozolin, chlorfenvinphos, pirimiphos-ethyl) commonly found in foods of central Italy.
The administration of the pesticide mixture dose dependently reduced benzo (a) pyrene hydroxylase, N-demethylase activities, glutathione peroxidase, glutathione reductase, glutathione-S-transferase and thiol transferase activities in the liver.
1(0,0,0,1) Details
17980473 Ncibi S, Ben Othman M, Akacha A, Krifi MN, Zourgui L: Opuntia ficus indica extract protects against chlorpyrifos-induced damage on mice liver. Food Chem Toxicol. 2008 Feb;46(2):797-802. Epub 2007 Sep 14.

Liver damage was evaluated by the measure of its weight and the quantification of some biochemical parameters, such as alanine amino transferase (ALAT), aspartate amino transferase (ASAT), phosphatase alkaline (PAL), lactate dehydrogenase (LDH), cholesterol and albumin in serum by spectrophotometric techniques.
1(0,0,0,1) Details
19801823 Tan DH, Peng SQ, Wu YL, Wang YM, Lu CF, Ding W, Wang QX, Yan CH: Chlorpyrifos induces delayed cytotoxicity after withdrawal in primary hippocampal neurons through extracellular signal-regulated kinase inhibition. Biol Pharm Bull. 2009 Oct;32(10):1649-55.

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12242675 Van Erp S, Booth L, Gooneratne R, O'Halloran K: Sublethal responses of wolf spiders (Lycosidae) to organophosphorous insecticides. Environ Toxicol. 2002 Oct;17(5):449-56.


Spiders were exposed to simulated field rates of two commercially available organophosphorous insecticides [Basudin (diazinon) and Lorsban (chlorpyrifos)] under laboratory conditions.
0(0,0,0,0) Details