| Name | pancreatic lipase |
|---|---|
| Synonyms | PL; PNLIP; Pancreatic lipase; Pancreatic triacylglycerol lipase; Pancreatic triacylglycerol lipase precursor; PL; Pancreatic lipases; Pancreatic triacylglycerol lipases… |
| Name | chlorpyrifos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 10561082 | Quistad GB, Casida JE: Sensitivity of blood-clotting factors and digestive enzymes to inhibition by organophosphorus pesticides. J Biochem Mol Toxicol. 2000;14(1):51-6. This study considers the relative organophosphate sensitivities of the aforementioned serine hydrolases compared with purified blood-clotting factors (thrombin, plasmin, and kallikrein) and digestive enzymes (alpha-chymotrypsin, trypsin, and elastase), assayed under similar conditions. Inhibitors that we examined are organophosphorus insecticides or their activated metabolites (paraoxon, chlorpyrifos oxon, and profenofos) and other toxicants (phenyl saligenin cyclic phosphonate and tribufos) for comparison with values that are found in the literature for the fluorophosphonates (isoflurophate and sarin). |
2(0,0,0,2) | Details |
| 16449251 | Quistad GB, Liang SN, Fisher KJ, Nomura DK, Casida JE: Each lipase has a unique sensitivity profile for organophosphorus inhibitors. Toxicol Sci. 2006 May;91(1):166-72. Epub 2006 Jan 31. Postheparin serum lipase, lipoprotein lipase (LPL) (two sources), pancreatic lipase, monoacylglycerol (MAG) lipase, cholesterol esterase, and KIAA1363 are considered with 32 OP pesticides and related compounds. Postheparin lipolytic activity in rat serum is inhibited by 14 OPs, including chlorpyrifos oxon (IC50 50-97 nM). |
2(0,0,0,2) | Details |