Protein Information

Name caspase (protein family or complex)
Synonyms caspase; caspases

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
20096330 Rush T, Liu XQ, Hjelmhaug J, Lobner D: Mechanisms of chlorpyrifos and diazinon induced neurotoxicity in cortical culture. Neuroscience. 2010 Mar 31;166(3):899-906. Epub 2010 Jan 20.

The toxicity of chlorpyrifos was attenuated by antagonists of either the NMDA or AMPA/kainate-type glutamate receptors, but the cell death was potentiated by the caspase inhibitor ZVAD.
31(0,1,1,1) Details
14976342 Newhouse K, Hsuan SL, Chang SH, Cai B, Wang Y, Xia Z: Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells. Toxicol Sci. 2004 May;79(1):137-46. Epub 2004 Feb 19.


Our results suggest that rotenone, at nanomolar concentrations, induces apoptosis in SH-SY5Y cells that is caspase-dependent.
2(0,0,0,2) Details
18155347 Saulsbury MD, Heyliger SO, Wang K, Round D: Characterization of chlorpyrifos-induced apoptosis in placental cells. Toxicology. 2008 Feb 28;244(2-3):98-110. Epub 2007 Oct 30.

0(0,0,0,0) Details
19167454 Saulsbury MD, Heyliger SO, Wang K, Johnson DJ: Chlorpyrifos induces oxidative stress in oligodendrocyte progenitor cells. Toxicology. 2009 May 2;259(1-2):1-9. Epub 2009 Jan 9.

0(0,0,0,0) Details