Protein Information

Name HC5
Synonyms CYCSP 1; CYCSP1; HC5; HCP36

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
12820996 van Beelen P, Verbruggen EM, Peijnenburg WJ: The evaluation of the equilibrium partitioning method using sensitivity distributions of species in water and soil. Chemosphere. 2003 Aug;52(7):1153-62.

For 10 organic substances (chlorpyrifos, atrazine, carbofuran, pentachlorophenol, chlordane, aldrin, trichlorobenzene, heptachlor, trichlorophenol and trichloroethene) and for 8 metals, sufficient data were available.
These over- or underestimations can have an impact on the setting of environmental quality standards which are based on the hazardous concentration 5% (HC5) values.
3(0,0,0,3) Details
17287007 Bollmohr S, Day JA, Schulz R: Temporal variability in particle-associated pesticide exposure in a temporarily open estuary, Western Cape, South Africa. Chemosphere. 2007 Jun;68(3):479-88. Epub 2007 Feb 6.

Particle-associated pesticides (chlorpyrifos, prothiofos, cypermethrin, fenvalerate, endosulfan and p,p-DDE) and physicochemical parameters (salinity, temperature, flow, and total organic content (TOC)) were measured in the Lourens River estuary (Western Cape) twice a month over a period of two years and equilibrium partitioning theory was applied to calculate concentrations of pesticides in the water.
Species sensitivity distribution indicated a 1.5-2.8 times higher toxicity (hazardous concentration HC5) for marine organisms compared to freshwater organisms.
1(0,0,0,1) Details
16986804 Frampton GK, Jansch S, Scott-Fordsmand JJ, Rombke J, Van den Brink PJ: Effects of pesticides on soil invertebrates in laboratory studies: a review and analysis using species sensitivity distributions. Environ Toxicol Chem. 2006 Sep;25(9):2480-9.

Based on a minimum of five species, the best available endpoint data (acute mortality median lethal concentration) enabled SSD and HC5 to be calculated for 11 pesticides (atrazine, carbendazim, chlorpyrifos, copper compounds, diazinon, dimethoate, gamma-hexachlorocyclohexane, lambda-cyhalothrin, parathion, pentachlorophenol, and propoxur).
8(0,0,1,3) Details
16986805 Jansch S, Frampton GK, Rombke J, Van den Brink PJ, Scott-Fordsmand JJ: Effects of pesticides on soil invertebrates in model ecosystem and field studies: a review and comparison with laboratory toxicity data. Environ Toxicol Chem. 2006 Sep;25(9):2490-501.

Ten pesticides had sufficient laboratory data to enable the observed higher-tier effects to be compared with 5% hazardous concentrations (HC5) estimated from acute toxicity laboratory data (atrazine, carbendazim, chlorpyrifos, diazinon, dimethoate, gamma-hexachlorocy-clohexane, lambda-cyhalothrin, parathion, pentachlorophenol, and propoxur).
7(0,0,1,2) Details