Protein Information

Name tumor necrosis factor
Synonyms Cachectin; DIF; TNF; TNF alpha; TNF a; TNFA; TNFSF 2; TNFSF2…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
10413184 Gordon CJ, Rowsey PJ: Are circulating cytokines interleukin-6 and tumor necrosis factor alpha involved in chlorpyrifos-induced fever?. Toxicology. 1999 May 3;134(1):9-17.
7(0,0,1,2) Details
10514030 Rowsey PJ, Gordon CJ: Tumor necrosis factor is involved in chlorpyrifos--induced changes in core temperature in the female rat. Toxicol Lett. 1999 Sep 20;109(1-2):51-9.
7(0,0,1,2) Details
18155347 Saulsbury MD, Heyliger SO, Wang K, Round D: Characterization of chlorpyrifos-induced apoptosis in placental cells. Toxicology. 2008 Feb 28;244(2-3):98-110. Epub 2007 Oct 30.

Chlorpyrifos-induced toxicity was characterized by the loss of mitochondrial potential, the appearance of nuclear condensation and fragmentation, down-regulation of Bcl-2 as well as up-regulation of TNFalpha and FAS mRNA.
6(0,0,1,1) Details