| Name | M2 muscarinic acetylcholine receptor |
|---|---|
| Synonyms | CHRM 2; CHRM2; HM2; M2 muscarinic acetylcholine receptor; Muscarinic M2 receptor; Muscarinic acetylcholine receptor M2; M2 muscarinic acetylcholine receptors; Muscarinic M2 receptors… |
| Name | chlorpyrifos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 18800293 | Udarbe Zamora EM, Liu J, Pope CN: Effects of chlorpyrifos oxon on M2 muscarinic receptor internalization in different cell types. J Toxicol Environ Health A. 2008;71(21):1440-7. The muscarinic M2 receptor is a member of the G protein-coupled receptor (GPCR) superfamily. |
1(0,0,0,1) | Details |
| 12937891 | Abou-Donia MB, Abdel-Rahman A, Goldstein LB, Dechkovskaia AM, Shah DU, Bullman SL, Khan WA: Sensorimotor deficits and increased brain nicotinic acetylcholine receptors following exposure to chlorpyrifos and/or in rats. Arch Toxicol. 2003 Aug;77(8):452-8. Epub 2003 Apr 26. This was further augmented with combined exposure, which caused a modest but significant increase in m2 muscarinic acetylcholine receptors (m2-mAChR) ligand binding in the cortex. |
1(0,0,0,1) | Details |
| 11275418 | Bomser JA, Casida JE: Diethylphosphorylation of rat cardiac M2 muscarinic receptor by chlorpyrifos oxon in vitro. Toxicol Lett. 2001 Feb 3;119(1):21-6. As a secondary effect, CPO is known to compete with agonist binding to the M2 muscarinic acetylcholine receptor (mAChR). |
1(0,0,0,1) | Details |
| 16256208 | Slotkin TA, Tate CA, Cousins MM, Seidler FJ: Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combination. Brain Res Dev Brain Res. 2005 Dec 7;160(2):219-30. Epub 2005 Oct 26. Terbutaline also reduced expression of m2 muscarinic acetylcholine receptors and suppressed their ability to inhibit AC. |
1(0,0,0,1) | Details |