| Name | beta adrenoceptors (protein family or complex) |
|---|---|
| Synonyms | Beta adrenoceptor; Beta adrenoceptor; Beta adrenergic receptor; Beta adrenergic receptors; Beta adrenoceptor; Beta adrenoceptors; Beta adrenoceptors |
| Name | chlorpyrifos |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16256208 | Slotkin TA, Tate CA, Cousins MM, Seidler FJ: Imbalances emerge in cardiac autonomic cell signaling after neonatal exposure to terbutaline or chlorpyrifos, alone or in combination. Brain Res Dev Brain Res. 2005 Dec 7;160(2):219-30. Epub 2005 Oct 26. In neonatal rats, we examined the effects of exposure to terbutaline, a beta-adrenoceptor (betaAR) agonist used to arrest preterm labor, and chlorpyrifos (CPF), a widely used organophosphate pesticide that acts in part through inhibition of cholinesterase, using scenarios mimicking the likely developmental stages corresponding to peak human exposures: postnatal days (PN) 2-5 for terbutaline and PN11-14 for CPF. |
81(1,1,1,1) | Details |
| 15710176 | Meyer A, Seidler FJ, Aldridge JE, Slotkin TA: Developmental exposure to terbutaline alters cell signaling in mature rat brain regions and augments the effects of subsequent neonatal exposure to the organophosphorus insecticide chlorpyrifos. Toxicol Appl Pharmacol. 2005 Mar 1;203(2):154-66. We examined the long-term effects of developmental exposure of rats to terbutaline, a beta-adrenoceptor agonist used to arrest preterm labor, and the organophosphorus insecticide chlorpyrifos (CPF) separately and together. |
81(1,1,1,1) | Details |
| 15963356 | Slotkin TA, Oliver CA, Seidler FJ: Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination. Brain Res Dev Brain Res. 2005 Jun 30;157(2):172-80. Terbutaline, which is chemically unrelated to CPF and which stimulates neuronal cell metabolism through direct actions on beta-adrenoceptors, also elicited oxidative damage in the developing brain with greater sensitivity in the second postnatal week. |
1(0,0,0,1) | Details |
| 16203236 | Slotkin TA, Brown KK, Seidler FJ: Developmental exposure of rats to chlorpyrifos elicits sex-selective hyperlipidemia and hyperinsulinemia in adulthood. Environ Health Perspect. 2005 Oct;113(10):1291-4. These outcomes and sex selectivity resemble earlier findings at the cellular level, which identified hepatic hyperresponsiveness to gluconeogenic inputs from beta-adrenoceptors or glucagon receptors. |
1(0,0,0,1) | Details |
| 14644659 | Meyer A, Seidler FJ, Cousins MM, Slotkin TA: Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target?. Environ Health Perspect. 2003 Dec;111(16):1871-6. In addition to basal AC activity, we assessed the AC response to direct enzymatic stimulants [forskolin, (Mn (2+))]; the response to isoproterenol, which activates signaling through beta-adrenoceptors (betaARs); and the concentration of betaAR binding sites. |
1(0,0,0,1) | Details |
| 10837889 | Auman JT, Seidler FJ, Slotkin TA: Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: implications for neurotoxicity. Brain Res Dev Brain Res. 2000 May 11;121(1):19-27. |
0(0,0,0,0) | Details |