Protein Information

Name constitutive androstane receptor
Synonyms CAR; CAR beta; CAR 1; CAR1; CARb; CARbeta; Constitutive activator of retinoid response; Constitutive active response…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
18832183 Baldwin WS, Roling JA: A concentration addition model for the activation of the constitutive androstane receptor by xenobiotic mixtures. Toxicol Sci. 2009 Jan;107(1):93-105. Epub 2008 Oct 1.

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20035023 Ellero S, Chakhtoura G, Barreau C, Langouet S, Benelli C, Penicaud L, Beaune P, de Waziers I: Xenobiotic-metabolizing cytochromes p450 in human white adipose tissue: expression and induction. Drug Metab Dispos. 2010 Apr;38(4):679-86. Epub 2009 Dec 24.


The WAT and liver models were then treated with typical P450 inducers (rifampicin, phenobarbital, and 2,3,7,8-tetrachlorodibenzo-p-dioxin) and lipophilic pollutants (lindane, prochloraz, and chlorpyrifos), and the effects on P450 expression were studied.
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