Protein Information

Name monoamine transporter
Synonyms Monoamine transporter; SLC18A2; SVAT; SVMT; Solute carrier family 18 member 2; Synaptic vesicular amine transporter; Synaptic vesicular amine transporter brain; Synaptic vesicular monoamine transporter brain…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
18835401 Slotkin TA, Seidler FJ: Developmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickel. Toxicol Appl Pharmacol. 2008 Dec 1;233(2):211-9. Epub 2008 Sep 16.

In contrast, Ni (2+) had completely distinct actions, suppressing tryptophan hydroxylase and enhancing the vesicular monoamine transporter, while also reducing 5HT receptor gene expression, effects that would tend to lower net 5HT function.
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