Protein Information

Name alkaline phosphatase
Synonyms ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase…

Compound Information

Name chlorpyrifos
CAS

Reference List

PubMed Abstract RScore(About this table)
20127145 Thengodkar RR, Sivakami S: Degradation of Chlorpyrifos by an alkaline phosphatase from the cyanobacterium Spirulina platensis. Biodegradation. 2010 Feb 3.
82(1,1,1,2) Details
17974266 Zhang YL, Mu W, Chen ZL, Han ZR, Ma C, Zhai RH: [Susceptibility and related physiological and biochemical mechanisms of Carposina niponensis Walsingham larvae on six insecticides before and after overwintering]. Ying Yong Sheng Tai Xue Bao. 2007 Aug;18(8):1913-6.

The study with impregnating method showed that after overwintering, the susceptibility of Carposina niponensis larvae on triazophos, phoxim, chlorpyrifos, malathion, lambda-cyhalothrin and abamectin was 34.50, 16.71, 3.89, 3.28, 5.90 and 2.73 times as much as that before overwintering, the total protein, glycogen and fat contents and carboxylesterase, acid phosphatase, alkaline phosphatase, glutathione-S-transferase, superoxide dismutase, catalase and peroxidase activities in C. niponensis larvae were decreased by 17.10%, 41.76% and 30.08%, 62.36%, 53.47%, 76.19%, 80.60%, 18.77%, 14.16% and 64.02%, respectively, and the activity of acetylcholinesterase, the target enzyme of many insecticides, was 1.41 times as much as that before overwintering.
31(0,1,1,1) Details
11051590 Goel A, Chauhan DP, Dhawan DK: Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study. Biol Trace Elem Res. 2000 May;74(2):171-83.

Similarly, a significant increase in the levels of various serum and liver marker enzymes (viz. alkaline phosphatase, aspartate aminotransferase [AST], and alanine aminotransferase [ALT]) was observed following treatment with chlorpyrifos.
7(0,0,1,2) Details
10025366 Gomes J, Dawodu AH, Lloyd O, Revitt DM, Anilal SV: Hepatic injury and disturbed amino acid metabolism in mice following prolonged exposure to organophosphorus pesticides. Hum Exp Toxicol. 1999 Jan;18(1):33-7.

Laboratory mice were exposed to a formulated mixture of the six organophosphorus pesticides (Dimethoate, Chlorpyrifos, Profenofos, Pirimiphos methyl, Triazophos and Dimethoate) most commonly used in agriculture in this region of the Middle East.
There were also non-significant increases in serum alkaline phosphatase, gama-glutamyl transpeptidase and some of the other amino acids.
1(0,0,0,1) Details
10995313 Alcocer MJ, Doyen C, Lee HA, Morgan MR: Properties of polyclonal, monoclonal, and recombinant antibodies recognizing the organophosphorus pesticide chlorpyrifos-ethyl. J Agric Food Chem. 2000 Sep;48(9):4053-9.

Furthermore, scFv gene sequences were linked directly to sequences coding for either a c-Myc tag, a His-tag, or alkaline phosphatase.
1(0,0,0,1) Details
10214458 Lakew K, Mekonnen Y: The health status of northern Omo State Farm workers exposed to chlorpyrifos and profenofos. Ethiop Med J. 1998 Jul;36(3):175-84.

Plasma alkaline phosphatase (AP) and glutamic pyruvic transaminase (GPT) values were estimated colorimetrically.
1(0,0,0,1) Details