Name | PN5 |
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Synonyms | NAV1.9; Na(V)1.9; PN5; Peripheral nerve sodium channel 5; SCN11A; SCN12A; SNS 2; SNS2… |
Name | chlorpyrifos |
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CAS |
PubMed | Abstract | RScore(About this table) | |
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10876030 | Dam K, Seidler FJ, Slotkin TA: Chlorpyrifos exposure during a critical neonatal period elicits gender-selective deficits in the development of coordination skills and locomotor activity. Brain Res Dev Brain Res. 2000 Jun 30;121(2):179-87. Administration of 1 mg/kg s.c. of chlorpyrifos on postnatal (PN) days 1-4 elicited deficits in reflex righting on PN3-4 and in geotaxic responses on PN5-8, an effect that was specific to females. |
6(0,0,1,1) | Details |
11882345 | Garcia SJ, Seidler FJ, Qiao D, Slotkin TA: Chlorpyrifos targets developing glia: effects on glial fibrillary acidic protein. Brain Res Dev Brain Res. 2002 Feb 28;133(2):151-61. Early postnatal (PN) CPF treatment (PN1-4) elicited effects only in the cerebellum of male rats; GFAP was suppressed initially (PN5) and showed a rebound elevation (PN10) before returning to normal values by PN30. |
1(0,0,0,1) | Details |
11557094 | Raines KW, Seidler FJ, Slotkin TA: Alterations in serotonin transporter expression in brain regions of rats exposed neonatally to chlorpyrifos. Brain Res Dev Brain Res. 2001 Sep 23;130(1):65-72. At the end of the treatment period (PN5 and 15, respectively) and 5-7 days later, we then examined the effects on paroxetine (PXT) binding to the presynaptic 5HT high-affinity transporter, a marker for (5HT) projections. |
1(0,0,0,1) | Details |
10837889 | Auman JT, Seidler FJ, Slotkin TA: Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: implications for neurotoxicity. Brain Res Dev Brain Res. 2000 May 11;121(1):19-27. On PN5, 24 h after the last dose, AC catalytic activity was induced as assessed by the response to the direct AC stimulant, Mn (2+). |
1(0,0,0,1) | Details |
11675126 | Navarro HA, Basta PV, Seidler FJ, Slotkin TA: Neonatal chlorpyrifos administration elicits deficits in immune function in adulthood: a neural effect?. Brain Res Dev Brain Res. 2001 Oct 24;130(2):249-52. |
0(0,0,0,0) | Details |