| Name | cytochrome P450 (protein family or complex) |
|---|---|
| Synonyms | cytochrome P450; cytochrome P 450; CYP450; CYP 450 |
| Name | dichlorvos |
|---|---|
| CAS | 2,2-dichloroethenyl dimethyl phosphate |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 1475794 | Yamano T, Morita S: Hepatotoxicity of trichlorfon and dichlorvos in isolated rat hepatocytes. . Toxicology. 1992 Nov 22;76(1):69-77. On the other hand, addition of antioxidants (diethyldithiocarbamate or N,N'-diphenyl-p-phenylenediamine), or cytochrome P-450 inhibitors (SKF-525A or to the incubation mixtures attenuated malondialdehyde production caused by dichlorvos and protected cells from death. |
31(0,1,1,1) | Details |
| 8644117 | Yamano T: Dissociation of DDVP-induced DNA strand breaks from oxidative damage in isolated rat hepatocytes. Toxicology. 1996 Apr 15;108(1-2):49-56. The number of these breaks was reduced by adding the cytochrome P450 inhibitor Dichlorvos (DDVP)-induced DNA single strand breaks were investigated in isolated rat hepatocytes. |
1(0,0,0,1) | Details |
| 6524963 | Purshottam T, Srivastava RK: Effect of high-fat and high-protein diets on toxicity of parathion and dichlorvos. Arch Environ Health. 1984 Nov-Dec;39(6):425-30. Hepatic microsomal cytochrome P-450 and aminopyrine demethylase activity were unchanged, but hydroxylase activity was increased significantly by HPD and HFD. |
1(0,0,0,1) | Details |
| 10826201 | Jensen SE: Mechanisms associated with methiocarb resistance in Frankliniella occidentalis (Thysanoptera: Thripidae). J Econ Entomol. 2000 Apr;93(2):464-71. Including the synergists piperonyl butoxide, a cytochrome P-450 monooxygenase inhibitor, or S,S,S-tributylphosphorotrithioate, an esterase inhibitor, in the methiocarb bioassays partially suppressed resistance in the most resistant populations. Assays of acetylcholinesterase sensitivity to inhibition by methiocarb, dichlorvos, and eserine suggested insensitive acetylcholinesterase in two of the resistant populations. |
1(0,0,0,1) | Details |
| 9931232 | Sturm A, Hansen P: Altered cholinesterase and monooxygenase levels in Daphnia magna and Chironomus riparius exposed to environmental pollutants. Ecotoxicol Environ Saf. 1999 Jan;42(1):9-15. These results suggest that cytochrome P450-dependent monooxygenase activities may be useful variables in toxicity tests with aquatic insects. Parathion, dichlorvos, and aldicarb caused dose-related inhibition of cholinesterase (ChE) in 24-h bioassays with both species. |
1(0,0,0,1) | Details |