Protein Information

Name cholinesterase
Synonyms Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase…

Compound Information

Name DDT
CAS 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene]

Reference List

PubMed Abstract RScore(About this table)
15250479 Lal CS, Kumar V, Ranjan A, Das VN, Kumar N, Kishore K, Bhattacharya SK: Evaluation of cholinesterase level in an endemic population exposed to malathion suspension formulation as a vector control measure. Mem Inst Oswaldo Cruz. 2004 Mar;99(2):219-21.

2(0,0,0,2) Details
18941829 Sole M, Hambach B, Cortijo V, Huertas D, Fernandez P, Company JB: Muscular and hepatic pollution biomarkers in the fishes Phycis blennoides and Micromesistius poutassou and the crustacean Aristeus antennatus in the Blanes Submarine Canyon (NW Mediterranean). Arch Environ Contam Toxicol. 2009 Jul;57(1):123-32. Epub 2008 Oct 22.


Several pollution biomarkers in muscle (activity of cholinesterases) and liver/hepatopancreas (catalase, glutathione S-transferases, carboxylesterases, ethoxyresorufin O-deethylase in fish or mixed function oxygenase (MFO)-related reductases in crustacean, and lipid peroxidation levels) were measured.
1(0,0,0,1) Details
15657813 Gill H, Williams TD, Bishop CA, Cheng KM, Elliott JE: Effects of azinphos-methyl on cholinergic responses and general health in zebra finches (Taeniopygia guttata) after previous treatment with p,p'-DDE. Arch Environ Contam Toxicol. 2005 Jan;48(1):118-26.

Extensive research has been conducted to determine the effects of currently used OPs on cholinesterase (ChE) activity; however, although OCs continue to be prevalent in areas of previous use, few studies have looked at the toxicity of a combination of residual OC compounds with currently used OP pesticides.
The focus of our study was to determine the effects of azinphos-methyl (a common OP used in apple orchards today) on ChE activity and general health in zebra finches (Taeniopygia guttata) previously exposed to p,p'-DDE (a commonly detected metabolite of DDT).
1(0,0,0,1) Details