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DDT

Identification (Source:EPA,EU)

ID	117
Name	DDT
CAS	50-29-3
IUPAC	1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane
Inchi	InChI=1S/C14H9Cl5/c15-11-5-1-9(2-6-11)13(14(17,18)19)10-3-7-12(16)8-4-10/h1-8,13H
CIPAC	3
EPA Code	029201
Formula	C14H9Cl5
SMILES	Clc1ccc(cc1)C(c2ccc(Cl)cc2)C(Cl)(Cl)Cl
Status	Not Approved

Classification

Mode of Action	Non-systemic stomach and contact action. Sodium channel modulator.
Pesticide Type	Insecticide
Chemical Group	Organochlorine
Classification	organochlorine acaricides bridged diphenyl acaricides organochlorine insecticides

Properties (Source:PubChem)

Molecular Weight	354.49
Physical State	White crystalline powder
AlogP	6.331
H-Bond Donor	0
H-Bond Acceptor	0
Surface Area	300.29
Polar Surface Area	0.0

Structure

Ecotoxicology (Source:PPDB,IPM)

Species	Method	Study Time	Dose Type	Value
Aquatic invertebrates	Acute	48 hour	EC50	0.005 mg l-1
Birds	Acute		LD50	2240 mg kg-1
Fish	Acute	96 hour	LC50	7 mg l-1
Honeybees	Acute	48 hour	LD50	5 μg bee-1
Mammals	Acute oral		LD50	113 mg kg-1
Mammals	Short term dietary		NOEL	1 ppm diet
Sediment dwelling organisms	Acute	96 hour	LC50	2.7 mg l-1
	Bio-concentration factor		BCF	3173
	Bio-concentration factor		CT50	Not available days

Related targets

Target Name	RScore (About this table)
progesterone receptor	85(1,1,1,5)	Details
thymidylate synthases	82(1,1,1,2)	Details
Cl 2	81(1,1,1,1)	Details
IL 1beta	33(0,1,1,3)	Details
C18	32(0,1,1,2)	Details
estrogen receptors	106(0,0,0,106)	Details
sodium channel (protein family or complex)	45(0,0,1,40)	Details
glutathione S transferase	42(0,0,0,42)	Details
cytochrome P450 (protein family or complex)	38(0,0,0,38)	Details
Acetylcholinesterase	34(0,0,0,34)	Details
Myosin	32(0,0,0,32)	Details
muscles	26(0,0,0,26)	Details
CYP3A4	23(0,0,0,23)	Details
CYP1A1	20(0,0,0,20)	Details
PCNA	18(0,0,0,18)	Details
SPMD	17(0,0,0,17)	Details
MDM2	15(0,0,0,15)	Details
androgen receptors	15(0,0,0,15)	Details
p38	14(0,0,0,14)	Details
pg m	14(0,0,0,14)	Details
glutathione transferases	13(0,0,0,13)	Details
catalase	13(0,0,0,13)	Details
AhR	12(0,0,0,12)	Details
ERbeta	11(0,0,0,11)	Details
thyroid stimulating hormone (protein family or complex)	11(0,0,0,11)	Details
ATPase	11(0,0,0,11)	Details
AP 1 (protein family or complex)	10(0,0,0,10)	Details
pc 1	10(0,0,0,10)	Details
GSTT1	10(0,0,0,10)	Details
dynorphin	9(0,0,0,9)	Details
Avian	9(0,0,0,9)	Details
WSTF	9(0,0,0,9)	Details
pregnane X receptor	9(0,0,0,9)	Details
activator protein 1	8(0,0,0,8)	Details
mitogen activated protein kinase (protein family or complex)	8(0,0,0,8)	Details
chitinase	8(0,0,0,8)	Details
caspase 3	8(0,0,0,8)	Details
NP I	8(0,0,0,8)	Details
KRAS	8(0,0,0,8)	Details
sex hormone binding globulin	8(0,0,0,8)	Details
SERS	7(0,0,1,2)	Details
GSTP1	7(0,0,0,7)	Details
RAPTOR	6(0,0,0,6)	Details
acetylcholine receptor (protein family or complex)	6(0,0,0,6)	Details
ace 1	6(0,0,0,6)	Details
follicle stimulating hormone (protein family or complex)	6(0,0,0,6)	Details
constitutive androstane receptor	6(0,0,0,6)	Details
HEPT	6(0,0,0,6)	Details
vascular endothelial growth factor	6(0,0,0,6)	Details
PFAS	6(0,0,0,6)	Details
Connexin 43	5(0,0,0,5)	Details
transferase	5(0,0,0,5)	Details
P glycoprotein	5(0,0,0,5)	Details
beta is	5(0,0,0,5)	Details
hormone receptor	5(0,0,0,5)	Details
NF kappa B	5(0,0,0,5)	Details
thyroperoxidase	5(0,0,0,5)	Details
TRbeta	5(0,0,0,5)	Details
EPOX	5(0,0,0,5)	Details
homeobox	5(0,0,0,5)	Details
CYP26	5(0,0,0,5)	Details
POLL	5(0,0,0,5)	Details
CECR2	5(0,0,0,5)	Details
TSHbeta	5(0,0,0,5)	Details
GPR30	5(0,0,0,5)	Details
RITA	5(0,0,0,5)	Details
RNF8	5(0,0,0,5)	Details
MMS2	5(0,0,0,5)	Details
superoxide dismutase	4(0,0,0,4)	Details
DRD4	4(0,0,0,4)	Details
ERK1	4(0,0,0,4)	Details
protein kinase C (protein family or complex)	4(0,0,0,4)	Details
cholinesterase	4(0,0,0,4)	Details
casein	4(0,0,0,4)	Details
CD4	4(0,0,0,4)	Details
adenosine A1 receptor	4(0,0,0,4)	Details
IL 6	4(0,0,0,4)	Details
CD8	4(0,0,0,4)	Details
PF6	4(0,0,0,4)	Details
F12	4(0,0,0,4)	Details
N cadherin	4(0,0,0,4)	Details
phospholamban	4(0,0,0,4)	Details
P100	4(0,0,0,4)	Details
UBC13	4(0,0,0,4)	Details
DRD2	4(0,0,0,4)	Details
zonula occludens 1	4(0,0,0,4)	Details

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