| Name | Acetylcholinesterase |
|---|---|
| Synonyms | ACHE; ACHE protein; AChE; ARACHE; AcChoEase; Acetylcholine acetylhydrolase; Acetylcholinesterase; Acetylcholinesterase isoform E4 E6 variant… |
| Name | DDT |
|---|---|
| CAS | 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene] |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19995666 | Ricciardi F, Matozzo V, Binelli A, Marin MG: Biomarker responses and contamination levels in crabs (Carcinus aestuarii) from the Lagoon of Venice: An integrated approach in biomonitoring estuarine environments. Water Res. 2009 Nov 26. The shore crab Carcinus aestuarii, sampled in the Lagoon of Venice (NE Italy), was used as a biomonitor species, and the chemical concentrations of 42 organic pollutants (HCHs, PAHs, PCBs, DDTs, PBDEs), biological responses related to neurotoxicity (AChE inhibition), detoxification mechanisms (CYP450 induction) and endocrine alterations (vitellogenin-like protein induction) were measured at the same time. |
1(0,0,0,1) | Details |
| 18405930 | Okoye PN, Brooke BD, Koekemoer LL, Hunt RH, Coetzee M: Characterisation of DDT, pyrethroid and resistance in Anopheles funestus from Obuasi, Ghana. Trans R Soc Trop Med Hyg. 2008 Jun;102(6):591-8. Epub 2008 Apr 10. Furthermore, an altered acetylcholinesterase conferring resistance was evident. |
1(0,0,0,1) | Details |
| 19274371 | Fonseca-Gonzalez I, Quinones ML, McAllister J, Brogdon WG: Mixed-function oxidases and esterases associated with cross-resistance between DDT and lambda-cyhalothrin in Anopheles darlingi Root 1926 populations from Colombia. Mem Inst Oswaldo Cruz. 2009 Feb;104(1):18-26. Enzyme levels related to insecticide resistance, including mixed function oxidases (MFO), non-specific esterases (NSE), glutathione S-transferases and modified acetylcholinesterase were evaluated in all populations and compared with a susceptible natural strain. |
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| 19941598 | Vezenegho SB, Brooke BD, Hunt RH, Coetzee M, Koekemoer LL: Malaria vector composition and insecticide susceptibility status in Guinea Conakry, West Africa. Med Vet Entomol. 2009 Dec;23(4):326-34. Biochemical enzyme analysis showed that an altered acetylcholinesterase is operating in the field at low levels. |
1(0,0,0,1) | Details |
| 17427696 | N'Guessan R, Corbel V, Bonnet J, Yates A, Asidi A, Boko P, Odjo A, Akogbeto M, Rowland M: Evaluation of indoxacarb, an oxadiazine insecticide for the control of pyrethroid-resistant Anopheles gambiae (Diptera: Culicidae). J Med Entomol. 2007 Mar;44(2):270-6. Performance against An. gambiae bearing kdr (pyrethroid and DDT resistance) or Ace-1R insensitive acetylcholinesterase (organophosphate and resistance) mechanisms was studied using larval and adult bioassays and a simulated experimental hut system (tunnel tests) that allows fuller expression of the behavioral responses to insecticide. |
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| 17973989 | Casimiro SL, Hemingway J, Sharp BL, Coleman M: Monitoring the operational impact of insecticide usage for malaria control on Anopheles funestus from Mozambique. Malar J. 2007 Oct 31;6:142. This is probably due to significantly elevated levels of Acetylcholinesterase levels found in the same populations. |
1(0,0,0,1) | Details |
| 19303125 | Ramphul U, Boase T, Bass C, Okedi LM, Donnelly MJ, Muller P: Insecticide resistance and its association with target-site mutations in natural populations of Anopheles gambiae from eastern Uganda. Trans R Soc Trop Med Hyg. 2009 Nov;103(11):1121-6. Epub 2009 Mar 19. Using molecular diagnostics, susceptible and resistant specimens were further tested for the presence of knockdown resistance (kdr) and acetylcholinesterase 1 resistance (ace-1 (R)) alleles. |
1(0,0,0,1) | Details |
| 19297972 | Gurusubramanian G, Rahman A, Sarmah M, Ray S, Bora S: Pesticide usage pattern in tea ecosystem, their retrospects and alternative measures. J Environ Biol. 2008 Nov;29(6):813-26. Due to this practice, the tea pests showed a higher tolerance/ resistance status due to formation of greater amount of esterases, glutathione S-transferase and acetylcholinesterase. |
1(0,0,0,1) | Details |
| 17067049 | Zayed AB, Szumlas DE, Hanafi HA, Fryauff DJ, Mostafa AA, Allam KM, Brogdon WG: Use of bioassay and microplate assay to detect and measure insecticide resistance in field populations of Culex pipiens from filariasis endemic areas of Egypt. J Am Mosq Control Assoc. 2006 Sep;22(3):473-82. Microplate assays were performed to measure levels of beta esterase, acetylcholinesterase, insensitive acetylcholinesterase, oxidases, and glutathione-S-transferase enzymes. |
1(0,0,0,1) | Details |
| 18817564 | Dabire KR, Diabate A, Djogbenou L, Ouari A, N'Guessan R, Ouedraogo JB, Hougard JM, Chandre F, Baldet T: Dynamics of multiple insecticide resistance in the malaria vector Anopheles gambiae in a rice growing area in South-Western Burkina Faso. Malar J. 2008 Sep 25;7:188. Cross-resistance to DDT and pyrethroids was conferred by alterations at site of action in the sodium channel, the - kdr mutation; resistance to organophosphates and carbamates resulted from a single point mutation in the oxyanion hole of the acetylcholinesterase enzyme designed as ace-1R. |
1(0,0,0,1) | Details |
| 16619611 | Casimiro S, Coleman M, Hemingway J, Sharp B: Insecticide resistance in Anopheles arabiensis and Anopheles gambiae from Mozambique. J Med Entomol. 2006 Mar;43(2):276-82. Increased frequencies of insecticide insensitive acetylcholinesterase, the target site for carbamates and organophosphates, were found in 16 of the populations tested. |
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| 16263378 | Binelli A, Ricciardi F, Riva C, Provini A: Screening of POP pollution by AChE and EROD activities in Zebra mussels from the Italian Great Lakes. Chemosphere. 2005 Dec;61(8):1074-82. Epub 2005 Apr 25. |
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| 16085276 | Binelli A, Ricciardi F, Riva C, Provini A: New evidences for old biomarkers: effects of several xenobiotics on EROD and AChE activities in Zebra mussel (Dreissena polymorpha). Chemosphere. 2006 Jan;62(4):510-9. Epub 2005 Aug 8. |
3(0,0,0,3) | Details |
| 17564842 | Binelli A, Riva C, Provini A: Biomarkers in Zebra mussel for monitoring and quality assessment of Lake Maggiore (Italy). Biomarkers. 2007 Jul-Aug;12(4):349-68. Three different biomarkers (acetylcholinesterase (AChE), ethoxy resorufin-O-deethylase (EROD) and DNA strand breaks) were measured in Zebra mussel (Dreissena polymorpha) specimens collected in April 2005 at six different sampling sites on Lake Maggiore, the second largest Italian lake in terms of depth and volume, in order to assess the spatial variation of exposure to man-made contaminants. |
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| 18755020 | Perera MD, Hemingway J, Karunaratne SP: Multiple insecticide resistance mechanisms involving metabolic changes and insensitive target sites selected in anopheline vectors of malaria in Sri Lanka. Malar J. 2008 Aug 28;7:168. The presence of metabolic resistance by esterase, glutathione S-transferase (GST) and monooxygenase-based mechanisms, and the sensitivity of the acetylcholinesterase target site were assessed using synergists, and biochemical, and metabolic techniques. |
2(0,0,0,2) | Details |
| 16865602 | Rakotondravelo ML, Anderson TD, Charlton RE, Zhu KY: Sublethal effects of three pesticides on activities of selected target and detoxification enzymes in the aquatic midge, Chironomus tentans (diptera: chironomidae). Arch Environ Contam Toxicol. 2006 Oct;51(3):360-6. Epub 2006 Jul 21. Sublethal effects of three pesticides including atrazine (triazine herbicide), DDT (organochlorinated insecticide), and chlorpyrifos (organophosphate insecticide) on acetylcholinesterase (AChE), general esterase (GE), glutathione S-transferase (GST), and cytochrome P450 monooxygenase (P450) activities were evaluated in the aquatic midge Chironomus tentans. |
2(0,0,0,2) | Details |
| 17710279 | Dzul FA, Patricia Penilla R, Rodriguez AD: [Susceptibility and insecticide resistance mechanisms in Anopheles albimanus from the southern Yucatan Peninsula, Mexico]. Salud Publica Mex. 2007 Jul-Aug;49(4):302-11. The frequency of An. albimanus with altered acetylcholinesterase (AChE) was high in La Union (33%). |
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| 15476966 | Foil LD, Coleman P, Eisler M, Fragoso-Sanchez H, Garcia-Vazquez Z, Guerrero FD, Jonsson NN, Langstaff IG, Li AY, Machila N, Miller RJ, Morton J, Pruett JH, Torr S: Factors that influence the prevalence of acaricide resistance and tick-borne diseases. Vet Parasitol. 2004 Oct 28;125(1-2):163-81. Acetylcholine esterase affinity for OPs is changed in resistant tick populations. |
2(0,0,0,2) | Details |
| 19038063 | Munhenga G, Masendu HT, Brooke BD, Hunt RH, Koekemoer LK: Pyrethroid resistance in the major malaria vector Anopheles arabiensis from Gwave, a malaria-endemic area in Zimbabwe. Malar J. 2008 Nov 28;7:247. Biochemical assays were used to determine the relative levels of detoxifying enzyme systems including non-specific esterases, monooxygenases and glutathione-S-transferases as well as to detect the presence of an altered acetylcholine esterase (AChE). |
1(0,0,0,1) | Details |
| 16619610 | Casimiro S, Coleman M, Mohloai P, Hemingway J, Sharp B: Insecticide resistance in Anopheles funestus (Diptera: Culicidae) from Mozambique. J Med Entomol. 2006 Mar;43(2):267-75. Low levels of insecticide-insensitive acetylcholinesterase, the target site for carbamates and organophosphates, were found in all populations tested. |
1(0,0,0,1) | Details |
| 16966160 | Binelli A, Ricciardi F, Riva C, Provini A: Integrated use of biomarkers and bioaccumulation data in Zebra mussel (Dreissena polymorpha) for site-specific quality assessment. Biomarkers. 2006 Sep-Oct;11(5):428-48. In this study, several persistent organic pollutants -- 23 polychlorinated biphenyl (PCB) congeners, 11 polycyclic aromatic hydrocarbons (PAHs), six dichlorodiphenyltricholroethane (DDT) relatives, hexachlorobenzene (HCB), chlorpyrifos and its oxidized metabolite -- and some herbicides (lindane and the isomers alpha, beta, delta; terbutilazine; alachlor; metolachlor) were measured in the soft tissues of the freshwater mollusc Zebra mussel (Dreissena polymorpha) from 25 sampling sites in the Italian portions of the sub-alpine great lakes along with the measure of ethoxyresorufin dealkylation (EROD) and acetylcholinesterase (AChE) activity. |
1(0,0,0,1) | Details |
| 17466253 | N'Guessan R, Boko P, Odjo A, Akogbeto M, Yates A, Rowland M: Chlorfenapyr: a pyrrole insecticide for the control of pyrethroid or DDT resistant Anopheles gambiae (Diptera: Culicidae) mosquitoes. Acta Trop. 2007 Apr;102(1):69-78. Epub 2007 Mar 12. Performance against An. gambiae bearing kdr (pyrethroid and DDT resistance) or Ace-1 (R) insensitive acetylcholinesterase (organophosphate and resistance) mechanisms was studied using a variety of adult bioassay tests including a simulated-experimental hut system (tunnel tests) that allows uninhibited mosquito behaviour/insecticide interactions. |
1(0,0,0,1) | Details |
| 19655174 | Fonseca-Gonzalez I, Cardenas R, Quinones ML, McAllister J, Brogdon WG: Pyrethroid and organophosphates resistance in Anopheles (N.) nuneztovari Gabaldon populations from malaria endemic areas in Colombia. Parasitol Res. 2009 Oct;105(5):1399-409. Epub 2009 Aug 5. Evidence is presented for low-level initial selection of some resistance mechanisms such as mixed-function oxidases and modified acetylcholinesterase. |
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