| Name | IL 6 |
|---|---|
| Synonyms | 26 kd protein; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; HGF… |
| Name | DDT |
|---|---|
| CAS | 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene] |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 14668922 | Weglarz L, Dzierzewicz Z, Skop B, Orchel A, Parfiniewicz B, Wisniowska B, Swiatkowska L, Wilczok T: Desulfovibrio desulfuricans lipopolysaccharides induce endothelial cell IL-6 and IL-8 secretion and E-selectin and VCAM-1 expression. Cell Mol Biol Lett. 2003;8(4):991-1003. Confluent monolayers of HUVEC were incubated in the absence or presence of 20 microg/ml and 60 microg/ml LPSs derived from the DdT and DdA bacterial strains. |
2(0,0,0,2) | Details |
| 15104118 | Kim JY, Choi CY, Lee KJ, Shin DW, Jung KS, Chung YC, Lee SS, Shin JG, Jeong HG: Induction of inducible synthase and proinflammatory cytokines expression by o,p'-DDT in macrophages. Toxicol Lett. 2004 Mar 7;147(3):261-9. This study investigated the effects of o,p'-DDT on the production of (NO) and proinflammatory cytokines (IL-1beta, IL-6, TNF-alpha) and analyzed the molecular mechanism in mouse macrophages. |
1(0,0,0,1) | Details |
| 17035600 | Medina-Diaz IM, Arteaga-Illan G, de Leon MB, Cisneros B, Sierra-Santoyo A, Vega L, Gonzalez FJ, Elizondo G: Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis (p-chlorophenyl) ethane. Drug Metab Dispos. 2007 Jan;35(1):95-102. Epub 2006 Oct 11. At higher doses, a decrease of CYP3A4 inducibility was observed together with an increase in levels of interleukin 6 mRNA, a proinflammatory cytokine that strongly represses CYP3A4 transcription. |
1(0,0,0,1) | Details |