Protein Information

Name IL 1beta
Synonyms Catabolin; IL 1; IL 1 beta; IL 1B; IL1 beta; IL1B; IL1F2; Interleukin 1…

Compound Information

Name DDT
CAS 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene]

Reference List

PubMed Abstract RScore(About this table)
15104118 Kim JY, Choi CY, Lee KJ, Shin DW, Jung KS, Chung YC, Lee SS, Shin JG, Jeong HG: Induction of inducible nitric oxide synthase and proinflammatory cytokines expression by o,p'-DDT in macrophages. Toxicol Lett. 2004 Mar 7;147(3):261-9.


This study investigated the effects of o,p'-DDT on the production of nitric oxide (NO) and proinflammatory cytokines (IL-1beta, IL-6, TNF-alpha) and analyzed the molecular mechanism in mouse macrophages.
1(0,0,0,1) Details
17530090 Jabbar MA, Shimakoshi H, Hisaeda Y: Enhanced reactivity of hydrophobic vitamin B12 towards the dechlorination of DDT in ionic liquid. Chem Commun. 2007 Apr 28;(16):1653-5. Epub 2007 Mar 23.

The electrolytic reductive dechlorination of 1,1-bis (p-chlorophenyl)-2,2,2-trichloroethane (DDT) in the ionic liquid (IL) 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF (4)]) in the presence of a cobalamin derivative afforded 1,1'-(ethylidene) bis (4-chlorobenzene)(DDO) and 1,1'-(ethenylidene) bis (4-chlorobenzene)(DDNU) with 1,1'-(2-chloroethylidene) bis (4-chlorobenzene)(DDMS); the enhanced reactivity, as well as the recyclability of the cobalamin derivative catalyst in IL, makes the present system more efficient for the development of "green" technologies.
31(0,1,1,1) Details
14668922 Weglarz L, Dzierzewicz Z, Skop B, Orchel A, Parfiniewicz B, Wisniowska B, Swiatkowska L, Wilczok T: Desulfovibrio desulfuricans lipopolysaccharides induce endothelial cell IL-6 and IL-8 secretion and E-selectin and VCAM-1 expression. Cell Mol Biol Lett. 2003;8(4):991-1003.

Confluent monolayers of HUVEC were incubated in the absence or presence of 20 microg/ml and 60 microg/ml LPSs derived from the DdT and DdA bacterial strains.
Also, the simultaneous stimulation of cells with LPSs and IL-1beta was evaluated.
1(0,0,0,1) Details