| Name | ERK1 |
|---|---|
| Synonyms | ERK 1; ERK1; ERT 2; ERT2; Extracellular signal regulated kinase 1; Extracellular signal related kinase 1b; Extracellular signal related kinase 1c; HS44KDAP… |
| Name | DDT |
|---|---|
| CAS | 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene] |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19828838 | Jajoo S, Mukherjea D, Kumar S, Sheth S, Kaur T, Rybak LP, Ramkumar V: Role of beta-arrestin1/ERK MAP kinase pathway in regulating adenosine A1 receptor desensitization and recovery. Am J Physiol Cell Physiol. 2010 Jan;298(1):C56-65. Epub 2009 Oct 14. Knockdown of beta-arrestin1 by short interfering RNA (siRNA) blocked R-PIA-mediated downregulation of the A (1) AR, suppressed R-PIA-dependent ERK1/2 and activator protein-1 (AP-1) activity, and reduced the induction of A (1) AR mRNA. |
3(0,0,0,3) | Details |
| 16322354 | Jajoo S, Mukherjea D, Pingle S, Sekino Y, Ramkumar V: Induction of adenosine A1 receptor expression by pertussis toxin via an ribosylation-independent pathway. J Pharmacol Exp Ther. 2006 Apr;317(1):1-10. Epub 2005 Dec 1. To test this hypothesis, we used hamster ductus deferens tumor (DDT (1) MF-2) cells, a cell culture model for studying A (1) AR, and showed that pertussis toxin (100 ng/ml) produced a time-dependent loss in A (1) AR-G (i) interaction and abolished A (1) AR activation of extracellular signal-regulated kinase 1/2. |
1(0,0,0,1) | Details |