| Name | hormone receptor |
|---|---|
| Synonyms | Early response protein NAK1; GFRP 1; GFRP1; Growth factor inducible nuclear protein N10; Growth factor response protein 1; HMR; Hormone receptor; N10… |
| Name | DDT |
|---|---|
| CAS | 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene] |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19031103 | Itoh H, Iwasaki M, Hanaoka T, Kasuga Y, Yokoyama S, Onuma H, Nishimura H, Kusama R, Tsugane S: Serum organochlorines and breast cancer risk in Japanese women: a case-control study. Cancer Causes Control. 2009 Jul;20(5):567-80. Epub 2008 Nov 25. Odds ratios of breast cancer or its hormone-receptor-defined subtypes according to serum organochlorines were calculated. |
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| 15483189 | Sonneveld E, Jansen HJ, Riteco JA, Brouwer A, van der Burg B: Development of androgen- and -responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays. Toxicol Sci. 2005 Jan;83(1):136-48. Epub 2004 Oct 13. This cell line was characterized by its stable expression of AR protein, its highly selective response to low levels of different natural and synthetic androgens, and its insignificant response to other nuclear hormone receptor ligands such as estrogens, progestins, and glucocorticoids. |
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| 16337670 | Hoekstra PF, Burnison BK, Garrison AW, Neheli T, Muir DC: Estrogenic activity of dicofol with the human estrogen receptor: Isomer- and enantiomer-specific implications. Chemosphere. 2006 Jun;64(1):174-7. Epub 2005 Dec 7. In this study, we examined the isomer- and enantiomer-specific endocrine disruption potential of dicofol using yeast-based steroid hormone receptor gene transcription assay designed with the human estrogen receptor (hER). |
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| 15597889 | Thomas P, Doughty K: Disruption of rapid, nongenomic steroid actions by environmental chemicals: interference with stimulation of sperm motility in Atlantic croaker. Environ Sci Technol. 2004 Dec 1;38(23):6328-32. The antagonistic actions of o,p'-DDT were partially reversed with 10-fold higher concentrations of 20beta-S, which is consistent with a hormone receptor-mediated mechanism of DDT action. |
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| 18762293 | Hjelmborg PS, Andreassen TK, Bonefeld-Jorgensen EC: Cellular uptake of lipoproteins and persistent organic compounds--an update and new data. Environ Res. 2008 Oct;108(2):192-8. Epub 2008 Aug 30. A number of POPs including the pesticide p,p'-dichlorodiphenyltrichloroethane (DDT), and especially its metabolite p,p'-dichlorodiphenyldichloroethene (DDE), interacts with nuclear hormone receptors causing these to malfunction, which in turn results in a range of deleterious health effects in humans. |
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