| Name | AhR |
|---|---|
| Synonyms | AHR; Ah receptor; AhR; Aryl hydrocarbon receptor; Aryl hydrocarbon receptor precursor; Dioxin receptor; Ah receptors; AhRs… |
| Name | DDT |
|---|---|
| CAS | 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene] |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17311112 | Ociepa-Zawal M, Rubis B, Lacinski M, Trzeciak WH: The effect of on the expression of CYP1A1, CYP1B1 and AhR genes and proliferation of MCF-7 cells. Acta Biochim Pol. 2007;54(1):113-7. Epub 2007 Feb 20. |
3(0,0,0,3) | Details |
| 16188257 | Elango A, Shepherd B, Chen TT: Effects of endocrine disrupters on the expression of growth hormone and prolactin mRNA in the rainbow trout pituitary. Gen Comp Endocrinol. 2006 Jan 15;145(2):116-27. Epub 2005 Sep 26. Co-incubation of pituitaries with TCDD and alpha-napthoflavone (ANF), which is an inhibitor of the aryl hydrocarbon receptor (AhR), caused an inhibition of TCDD-induced PRL mRNA at the higher and lower concentrations, but these effects were less consistent on GH mRNA levels. |
2(0,0,0,2) | Details |
| 16705413 | Noguerol TN, Boronat S, Casado M, Raldua D, Barcelo D, Pina B: Evaluating the interactions of vertebrate receptors with persistent pollutants and antifouling pesticides using recombinant yeast assays. Anal Bioanal Chem. 2006 Jul;385(6):1012-9. Epub 2006 May 17. In this work we use two yeast systems to test the ability of different chemicals to bind and activate two vertebrate receptors which are intimately related to adverse biological effects of pollution in exposed fauna: the estrogen receptor (ER) and the aryl hydrocarbon receptor (AhR). |
1(0,0,0,1) | Details |
| 18032409 | Rasier G, Parent AS, Gerard A, Denooz R, Lebrethon MC, Charlier C, Bourguignon JP: Mechanisms of interaction of endocrine-disrupting chemicals with -evoked secretion of gonadotropin-releasing hormone. Toxicol Sci. 2008 Mar;102(1):33-41. Epub 2007 Nov 20. A complete prevention of o,p'-DDT effects was caused by an estrogen receptor (ER) antagonist as well as an aryl hydrocarbon receptor (AHR) antagonist and inhibitors of protein kinases A and C and mitogen-activated kinases. |
1(0,0,0,1) | Details |
| 17654248 | Han EH, Jeong TC, Jeong HG: Methoxychlor suppresses the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible CYP1A1 expression in murine Hepa-1c1c7 cells. J Toxicol Environ Health A. 2007 Aug;70(15-16):1304-9. A transient transfection assay using dioxin-response element (DRE)-linked luciferase and an electrophoretic mobility shift assay revealed that MXC reduced the transformation of the aryl hydrocarbons (Ah) receptor to a form capable of specifically binding to the DRE sequence in the promoter region of the CYP1A1 gene. |
1(0,0,0,1) | Details |
| 18835349 | Minh SD, Below S, Muller C, Hildebrandt JP: Novel mammalian cell lines expressing reporter genes for the detection of environmental chemicals activating endogenous aryl hydrocarbon receptors (ArhR) or estrogen receptors (ER). Toxicol In Vitro. 2008 Dec;22(8):1935-47. Epub 2008 Sep 15. |
1(0,0,0,1) | Details |
| 17526421 | Niimi S, Kim EY, Iwata H, Watanabe MX, Yasunaga G, Fujise Y, Tanabe S: Identification and hepatic expression profiles of cytochrome P450 1-4 isozymes in common minke whales (Balaenoptera acutorostrata). Comp Biochem Physiol B Biochem Mol Biol. 2007 Aug;147(4):667-81. Epub 2007 Apr 14. CYP1A1 levels showed a positive correlation with CYP1A2 levels (r=0.64, p <0.01) indicating that both CYP isozymes were regulated by aryl hydrocarbon receptor activated by endogenous ligands. |
1(0,0,0,1) | Details |
| 17665678 | Strause KD, Zwiernik MJ, Im SH, Bradley PW, Moseley PP, Kay DP, Park CS, Jones PD, Blankenship AL, Newsted JL, Giesy JP: Risk assessment of great horned owls (Bubo virginianus) exposed to polychlorinated biphenyls and DDT along the Kalamazoo River, Michigan, USA. Environ Toxicol Chem. 2007 Jul;26(7):1386-98. Egg TEQ (WHO-Avian) calculated from aryl hydrocarbon receptor-active PCB congeners and WHO TEFs ranged to 8.0 and 1.9 x 10 (2) pg TEQ (WHO-Avian)/g, (wet wt) at the RA and combined KRSS, respectively. |
1(0,0,0,1) | Details |
| 16263378 | Binelli A, Ricciardi F, Riva C, Provini A: Screening of POP pollution by AChE and EROD activities in Zebra mussels from the Italian Great Lakes. Chemosphere. 2005 Dec;61(8):1074-82. Epub 2005 Apr 25. On the contrary, the enzyme activity in Lake Maggiore showed an interesting opposite effect of AhR-binding compounds and trace metals. |
1(0,0,0,1) | Details |