Protein Information

Name Avian
Synonyms Avian; C erbB 3; C erbB3; ERBB3; ERBB3 protein; ErbB 3; ErbB 3 R1; ErbB 3 R2…

Compound Information

Name DDT
CAS 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene]

Reference List

PubMed Abstract RScore(About this table)
16998635 Hothem RL, Crayon JJ, Law MA: Effects of contaminants on reproductive success of aquatic birds nesting at Edwards Air Force Base, California. Arch Environ Contam Toxicol. 2006 Nov;51(4):711-9. Epub 2006 Sep 4.


Avian reproduction was evaluated in 1999.
2(0,0,0,2) Details
17665678 Strause KD, Zwiernik MJ, Im SH, Bradley PW, Moseley PP, Kay DP, Park CS, Jones PD, Blankenship AL, Newsted JL, Giesy JP: Risk assessment of great horned owls (Bubo virginianus) exposed to polychlorinated biphenyls and DDT along the Kalamazoo River, Michigan, USA. Environ Toxicol Chem. 2007 Jul;26(7):1386-98.


The study examined risks from total PCBs, including 2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents (TEQWorld Health Organization [WHO]-Avian Toxicity Equivalency Factor [TEF]), and total DDTs (sum of DDT, dichlorodiphenyldichloroethylene [DDE], and dichlorodiphenyldichloroethane [DDD]; sigmaDDT) by measuring concentrations in eggs and nestling blood plasma in two regions of the KRSS (upper, lower) and an upstream reference area (RA).
2(0,0,0,2) Details
19117372 Kamata R, Shiraishi F, Takahashi S, Shimizu A, Shiraishi H: Reproductive and developmental effects of transovarian exposure to o,p'-DDT in Japanese quails. Environ Toxicol Chem. 2008 Dec 31:1.


Avian species have the possible risk of embryonic exposure to persistent, lipophilic environmental contaminants, such as DDT, by transfer of chemicals accumulated in mother birds to eggs.
1(0,0,0,1) Details
19422813 Valeron PF, Pestano JJ, Luzardo OP, Zumbado ML, Almeida M, Boada LD: Differential effects exerted on human mammary epithelial cells by environmentally relevant organochlorine pesticides either individually or in combination. Chem Biol Interact. 2009 Aug 14;180(3):485-91. Epub 2009 May 5.


Additionally, transcriptional regulation arrays showed that the exposure of HMEC to an environmentally relevant mixture of OCs (p,p'-DDD plus p,p'-DDE plus o,p'-DDE plus aldrin plus dieldrin) sharply upregulated the expression of a number of protein kinases genes, such as ACVRL1, ALK-1, KIT, ERBB3, and ALK-1 at concentrations close to those detected in human populations.
1(0,0,0,1) Details
19806454 Rajaei F, Esmaili-Sari A, Bahramifar N, Ghasempouri M, Savabieasfahani M: Avian liver organochlorine and PCB from South coast of the Caspian Sea, Iran. Ecotoxicology. 2010 Feb;19(2):329-37. Epub 2009 Oct 6.

1(0,0,0,1) Details
19391684 Kamata R, Shiraishi F, Takahashi S, Shimizu A, Shiraishi H: Reproductive and developmental effects of transovarian exposure to o,p'-DDT in Japanese quails. Environ Toxicol Chem. 2009 Apr;28(4):782-90.


Avian species have the possible risk of embryonic exposure to persistent, lipophilic environmental contaminants, such as dichlorodiphenyltrichloroethane (DDT), by transfer of chemicals accumulated in mother birds to eggs.
1(0,0,0,1) Details
19004475 Conder JM, Sorensen MT, Leitman P, Martello LB, Wenning RJ: Avian ecological risk potential in an urbanized estuary: Lower Hackensack River, New Jersey, USA. Sci Total Environ. 2009 Jan 15;407(3):1035-47. Epub 2008 Nov 11.

1(0,0,0,1) Details