| PubMed |
Abstract |
RScore(About this table) |
| 16817233 |
Espinoza-Fonseca LM, Trujillo-Ferrara JG: Conformational changes of the p53-binding cleft of MDM2 revealed by molecular dynamics simulations. Biopolymers. 2006 Nov;83(4):365-73.
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5(0,0,0,5) |
Details |
| 18355443 |
Espinoza-Fonseca LM, Garcia-Machorro J: Aromatic-aromatic interactions in the formation of the MDM2-p53 complex. . Biochem Biophys Res Commun. 2008 Jun 13;370(4):547-51. Epub 2008 Mar 18.
|
5(0,0,0,5) |
Details |
| 16174299 |
Espinoza-Fonseca LM: Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer. Theor Biol Med Model. 2005 Sep 20;2:38.
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4(0,0,0,4) |
Details |
| 16530164 |
Espinoza-Fonseca LM, Trujillo-Ferrara JG: Transient stability of the helical pattern of region F19-L22 of the N-terminal domain of p53: a molecular dynamics simulation study. Biochem Biophys Res Commun. 2006 Apr 28;343(1):110-6. Epub 2006 Mar 3.
The region F19-L22, which contains one of the most important residues needed for the interaction of p53 with MDM2, seems to be formed and stabilized by the existence of one hydrophobic and one aromatic cluster. |
1(0,0,0,1) |
Details |