| 18284681 |
Brun J, Chiu R, Lockhart K, Xiao W, Wouters BG, Gray DA: hMMS2 serves a redundant role in human PCNA polyubiquitination. BMC Mol Biol. 2008 Feb 19;9:24.
Monoubiquitination of PCNA is controlled by RAD18 (E3 ligase) and RAD6 (E2 conjugating enzyme), while the extension of the monoubiquitinated PCNA into a polyubiquitinated substrate is governed by RAD5, and the heterodimer of UBC13/MMS2. |
4(0,0,0,4) |
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| 18178771 |
Wen R, Torres-Acosta JA, Pastushok L, Lai X, Pelzer L, Wang H, Xiao W: Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response. Plant Cell. 2008 Jan;20(1):213-27. Epub 2008 Jan 4.
All four Uev1 proteins can replace yeast MMS2 DDT functions in vivo. |
1(0,0,0,1) |
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