Protein Information

Name GSTP1
Synonyms DFN 7; PI; DFN7; FAEES 3; FAEES3; GST class pi; GST3; GSTP 1…

Compound Information

Name DDT
CAS 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene]

Reference List

PubMed Abstract RScore(About this table)
19057715 Morales E, Sunyer J, Castro-Giner F, Estivill X, Julvez J, Ribas-Fito N, Torrent M, Grimalt JO, de Cid R: Influence of glutathione S-transferase polymorphisms on cognitive functioning effects induced by p,p'-DDT among preschoolers. Environ Health Perspect. 2008 Nov;116(11):1581-5. Epub 2008 Jul 30.


We hypothesized that genetic variability in glutathione S-transferase (GST) genes (GSTP1, GSTM1, and GSTT1) could influence the effects of prenatal exposure to p,p'-DDT.
5(0,0,0,5) Details
17373952 Matambo TS, Abdalla H, Brooke BD, Koekemoer LL, Mnzava A, Hunt RH, Coetzee M: Insecticide resistance in the malarial mosquito Anopheles arabiensis and association with the kdr mutation. Med Vet Entomol. 2007 Mar;21(1):97-102.


Comparisons between the unselected base colony and the DDT-resistant strain showed elevated glutathione-S-transferase (P <0.05) in both sexes and elevated esterases (P <0.05) in males only.
1(0,0,0,1) Details
19303595 Messaros BM, Rossano MG, Liu G, Diamond MP, Friderici K, Nummy-Jernigan K, Daly D, Puscheck E, Paneth N, Wirth JJ: Negative effects of serum p,p'-DDE on sperm parameters and modification by genetic polymorphisms. Environ Res. 2009 May;109(4):457-64. Epub 2009 Mar 20.


Serum was analyzed for organochlorines (OC) and DNA for polymorphisms in GSTM1, GSTT1, GSTP1 and CYP1A1.
1(0,0,0,1) Details