| Name | thyroid stimulating hormone (protein family or complex) |
|---|---|
| Synonyms | Thyroid stimulating hormone |
| Name | DDT |
|---|---|
| CAS | 1,1′-(2,2,2-trichloroethylidene)bis[4-chlorobenzene] |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19707252 | Lopez-Espinosa MJ, Vizcaino E, Murcia M, Fuentes V, Garcia AM, Rebagliato M, Grimalt JO, Ballester F: Prenatal exposure to organochlorine compounds and neonatal thyroid stimulating hormone levels. J Expo Sci Environ Epidemiol. 2009 Aug 26. |
2(0,0,0,2) | Details |
| 18550560 | Chevrier J, Eskenazi B, Holland N, Bradman A, Barr DB: Effects of exposure to polychlorinated biphenyls and organochlorine pesticides on thyroid function during pregnancy. Am J Epidemiol. 2008 Aug 1;168(3):298-310. Epub 2008 Jun 10. These compounds, as well as thyroid-stimulating hormone, total and free were measured in serum samples collected between October 1999 and October 2000 from 334 pregnant women living in the Salinas Valley, California. |
2(0,0,0,2) | Details |
| 16764480 | Mortensen AS, Arukwe A: The persistent DDT metabolite, 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene, alters thyroid hormone-dependent genes, hepatic cytochrome P4503A, and pregnane X receptor gene expressions in Atlantic salmon (Salmo salar) Parr. Environ Toxicol Chem. 2006 Jun;25(6):1607-15. Thyroid-stimulating hormone (TSHbeta), T4 deiodinase (T4ORD), thyroid receptors (TRalpha and TRbeta), and insulin-like growth factor type 1 receptor (IGF-1R) were analyzed using quantitative (real-time) polymerase chain reaction in liver, brain, and kidney, whereas cytochrome P4503A (CYP3A) and pregnane X receptor (PXR) mRNA levels were analyzed only in the liver. |
1(0,0,0,1) | Details |
| 17056472 | Mortensen AS, Kortner TM, Arukwe A: Thyroid hormone-dependent gene expression as a biomarker of short-term 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene (DDE) exposure in European common frog (Rana temporaria) tadpoles. Biomarkers. 2006 Nov-Dec;11(6):524-37. Expression patterns of genes encoding for growth hormone, thyroid-stimulating hormone (TSHbeta) and thyroid hormone receptor (TRalpha and TRbeta) isoforms were evaluated in the head, body and tail regions using a validated real-time polymerase chain reaction (PCR) method. |
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| 17521129 | Hall AJ, Thomas GO: Polychlorinated biphenyls, DDT, polybrominated diphenyl ethers, and organic pesticides in United Kingdom harbor seals (Phoca vitulina)--mixed exposures and thyroid homeostasis. Environ Toxicol Chem. 2007 May;26(5):851-61. Serum TT3 levels in the harbor seals with the highest exposures might be indicative of a T3 thyrotoxicosis, but without information on free T3 and circulating thyroid-stimulating hormone levels, it is difficult to determine the importance of this observation for the health of the individuals or populations. |
1(0,0,0,1) | Details |
| 20093282 | Chen M, Chiou P, Liao YH, Lin CM, Chen T: Development and characterization of five Rainbow Trout pituitary single-cell clone lines capable of producing pituitary hormones. J Endocrinol. 2010 Jan 21. Reverse transcription (RT)-PCR analysis revealed that, in addition to expressing growth hormone (GH), prolactin (PRL) and estradiol receptor alpha (E2Ralpha) genes, each single-cell clone line also expressed other pituitary specific genes such as thyroid stimulating hormone (TSH), gonadotropin I (GTH-1), gonadotropin II (GTH-2), somatolactin (SL), proopiomelanocortin-B (POMC-B) and corticoidsteroid receptor (CR). |
1(0,0,0,1) | Details |
| 16492389 | Asawasinsopon R, Prapamontol T, Prakobvitayakit O, Vaneesorn Y, Mangklabruks A, Hock B: The association between organochlorine and thyroid hormone levels in cord serum: a study from northern Thailand. Environ Int. 2006 May;32(4):554-9. Epub 2006 Feb 21. Umbilical cord blood was collected for measuring OCs, total lipids, and thyroid hormones, including total (TT (4)), free (FT (4)), and thyroid stimulating hormone (TSH). 1,1-dichloro-2,2-di (4-chlorophenyl) ethylene (p,p'-DDE) had the highest level in all serum samples with a geometric mean of 1,191 ng/g lipids in maternal serum and 742 ng/g lipids in cord serum. |
1(0,0,0,1) | Details |
| 17189629 | Meeker JD, Altshul L, Hauser R: Serum PCBs, p,p'-DDE and HCB predict thyroid hormone levels in men. Environ Res. 2007 Jun;104(2):296-304. Epub 2006 Dec 26. Abbreviations: BMI, body mass index; CYP, cytochrome P450; DDT, 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane; HCB, hexachlorobenzene; MDL, method detection limit; NHANES, national health and nutrition examination survey: p,p (')-DDE, 1,1-dichloro-2,2-bis (p-chlorophenyl) ethylene; PCB, polychlorinated biphenyl; T (3), T (4), thryoxine; TSH, thyroid stimulating hormone (thyrotrophin); US, United States. |
1(0,0,0,1) | Details |
| 19766106 | Rossi M, Dimida A, Ferrarini E, Silvano E, De Marco G, Agretti P, Aloisi G, Simoncini T, Di Bari L, Tonacchera M, Giorgi F, Maggio R: Presence of a putative steroidal allosteric site on glycoprotein hormone receptors. Eur J Pharmacol. 2009 Nov 25;623(1-3):155-9. Epub 2009 Sep 17. In a previous work we found that the insecticide 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane (DDT), inhibits the accumulation of cAMP as induced by the bovine thyroid stimulating hormone (bTSH) in cells transfected with the TSH receptor. |
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