Protein Information

Name cytochrome P450 (protein family or complex)
Synonyms cytochrome P450; cytochrome P 450; CYP450; CYP 450

Compound Information

Name bifenthrin
CAS

Reference List

PubMed Abstract RScore(About this table)
19610439 Ramoutar D, Cowles RS, Alm SR: Pyrethroid resistance mediated by enzyme detoxification in Listronotus maculicollis (Coleoptera: Curculionidae) from Connecticut. J Econ Entomol. 2009 Jun;102(3):1203-8.

In this study, topical application bioassays with bifenthrin and bifenthrin combined with synergists affecting three detoxification systems were conducted on four field-collected adult populations of L. maculicollis from Connecticut to determined whether cytochrome P450 monooxgenases (P450s), glutathione S-transferases (GSTs), and/or carboxyl-esterases (COEs) mediated metabolic detoxification.
31(0,1,1,1) Details
20009351 Abdou R, Khalil W, Shah S, Murasawa Y, Sasaki K, Shimoda M: Effects of Several Pyrethroids on Hepatic Cytochrome P450 Activities in Rats. J Vet Med Sci. 2009 Dec 10.

Four commonly used pyrethroids (permethrin, bifenthrin, ethofenprox, and fenpropathrin) were orally administered to Sprague-Dawley rats for 5 days to study their effects on the liver cytochrome P450 (CYP) activities.
7(0,0,1,2) Details
18948380 Scollon EJ, Starr JM, Godin SJ, DeVito MJ, Hughes MF: In vitro metabolism of pyrethroid pesticides by rat and human hepatic microsomes and cytochrome p450 isoforms. Drug Metab Dispos. 2009 Jan;37(1):221-8. Epub 2008 Oct 23.

The pyrethroids bifenthrin, S-bioallethrin, bioresmethrin, beta-cyfluthrin, cypermethrin, cis-permethrin, and trans-permethrin were incubated in rat and human hepatic microsomes in the presence or absence of NADPH.
2(0,0,0,2) Details