Name | RNase P (protein family or complex) |
---|---|
Synonyms | RNase P; Ribonuclease P |
Name | blasticidin-S |
---|---|
CAS |
PubMed | Abstract | RScore(About this table) | |
---|---|---|---|
12688530 | Kalavrizioti D, Vourekas A, Tekos A, Tsagla A, Stathopoulos C, Drainas D: Kinetics of inhibition of ribonuclease P activity by peptidyltransferase inhibitors. Mol Biol Rep. 2003 Mar;30(1):9-14. A cell-free system derived from Dictyostelium discoideum has been used to study the kinetics of inhibition of RNase P by puromycin, amicetin and blasticidin S. |
113(1,2,2,3) | Details |
16337609 | Hung CF, Cheng TL, Wu RH, Teng CF, Chang WT: A novel bidirectional expression system for simultaneous expression of both the protein-coding genes and short hairpin RNAs in mammalian cells. Biochem Biophys Res Commun. 2006 Jan 27;339(4):1035-42. Epub 2005 Dec 1. In mammals, the conserved poly (ADP- polymerase 2 (PARP-2)/RNase P bidirectional control promoter simultaneously expresses both the PARP-2 protein and RNase P RNA by RNA polymerase II- and III-dependent mechanisms, respectively. In addition, to extend its utility for the establishment of inherited stable clones, we have also reconstructed this bidirectional expression system with the blasticidin S deaminase gene, an effective dominant drug resistance selectable marker, and examined both the selection and inhibition efficiencies in drug resistance and gene expression. |
2(0,0,0,2) | Details |
11092557 | Stathopoulos C, Tsagla A, Tekos A, Drainas D: Effect of peptidyltransferase inhibitors on ribonuclease P activity from Dictyostelium discoideum. Mol Biol Rep. 2000 Jun;27(2):107-11. Effect of antibiotics on RNase P.. Among the inhibitors tested puromycin, amicetin and blasticidin S revealed a dose-dependent inhibition of tRNA maturation. |
1(0,0,0,1) | Details |