Protein Information

Name CYP2C19
Synonyms (R) limonene 6 monooxygenase; Flavoprotein linked monooxygenase; Mephenytoin 4 hydroxylase; (S) limonene 6 monooxygenase; (S) limonene 7 monooxygenase; CYP2C; CPCJ; CYP 2C…

Compound Information

Name carbosulfan
CAS

Reference List

PubMed Abstract RScore(About this table)
20307514 Abass K, Reponen P, Mattila S, Pelkonen O: Metabolism of carbosulfan II. Chem Biol Interact. 2010 Mar 20.

Significant correlations between carbosulfan activation and CYP marker activities were seen with CYP3A4 (omeprazole sulfoxidation), CYP2C19 (omeprazole 5-hydroxylation) and CYP3A4 (midazolam 1'-hydroxylation), displaying r (2)=0.96, 0.87 and 0.82, respectively.
162(2,2,2,2) Details